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Toll-Like Receptor 4 Signaling is Involved in IgA-Stimulated Mesangial Cell Activation

Lim BJ, Lee D, Hong SW, Jeong HJ

PURPOSE: Deposition of polymeric IgA1 in the kidney mesangium is the hallmark of IgA nephropathy, but the molecular mechanisms of IgA-mediated mesangial responses and inflammatory injuries remain poorly understood. We...
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