- Evaluation of Stem Cell Components in Retrocorneal Membranes
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Lee SH, Kim KW, Kim MK, Chun YS, Kim JC
- KMID: 1796949
- J Korean Med Sci.
- 2014 Jun;29(6):846-851.
- doi: 10.3346/jkms.2014.29.6.846
The purpose of this study was to elucidate the origin and cellular composition of retrocorneal membranes (RCMs) associated with chemical burns using immunohistochemical staining for primitive cell markers. Six cases... -
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- Overexpression of bone morphogenetic protein 4 in STO fibroblast feeder cells represses the proliferation of mouse embryonic stem cells in vitro
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Kim GH, Lee GR, Choi HI, Park NH, Chung HT, Han IS
- KMID: 1397450
- Exp Mol Med.
- 2012 Jul;44(7):457-463.
Embryonic stem cells (ESCs) can be propagated in vitro on feeder layers of mouse STO fibroblast cells. The STO cells secrete several cytokines that are essential for ESCs to maintain... -
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- Human telomerase catalytic subunit (hTERT) suppresses p53-mediated anti-apoptotic response via induction of basic fibroblast growth factor
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Jin X, Beck S, Sohn YW, Kim JK, Kim SH, Yin J, Pian X, Kim SC, Choi YJ, Kim H
- KMID: 1104384
- Exp Mol Med.
- 2010 Aug;42(8):574-582.
- doi: 10.3858/emm.2010.42.8.058
Although human telomerase catalytic subunit (TERT) has several cellular functions including telomere homeostasis, genomic stability, cell proliferation, and tumorigenesis, the molecular mechanism underlying anti-apoptosis regulated by TERT remains to be... -
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- Podoplanin, alpha-Smooth Muscle Actin or S100A4 Expressing Cancer-Associated Fibroblasts Are Associated with Different Prognosis in Colorectal Cancers
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Choi SY, Sung R, Lee SJ, Lee TG, Kim N, Yoon SM, Lee EJ, Chae HB, Youn SJ, Park SM
- KMID: 1793043
- J Korean Med Sci.
- 2013 Sep;28(9):1293-1301.
- doi: 10.3346/jkms.2013.28.9.1293
The interactions between the tumor microenvironment and tumor cells determine the behavior of the primary tumors. Whether cancer-associated fibroblasts (CAF) have a tumor progressive or a protective role likely depends... -
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- Disease-specific induced pluripotent stem cells: a platform for human disease modeling and drug discovery
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Jang J, Yoo JE, Lee JA, Lee DR, Kim JY, Huh YJ, Kim DS, Park CY, Hwang DY, Kim HS, Kang HC, Kim DW
- KMID: 1245263
- Exp Mol Med.
- 2012 Mar;44(3):202-213.
- doi: 10.3858/emm.2012.44.3.015
The generation of disease-specific induced pluripotent stem cell (iPSC) lines from patients with incurable diseases is a promising approach for studying disease mechanisms and drug screening. Such innovation enables to... -
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