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Added Value of Contrast-Enhanced Ultrasound on Biopsies of Focal Hepatic Lesions Invisible on Fusion Imaging Guidance

Kang TW, Lee MW, Song KD, Kim M, Kim SS, Kim SH, Ha SY

OBJECTIVE: To assess whether contrast-enhanced ultrasonography (CEUS) with Sonazoid can improve the lesion conspicuity and feasibility of percutaneous biopsies for focal hepatic lesions invisible on fusion imaging of real-time ultrasonography...
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Comparison of the Efficacies of Parenteral Iron Sucrose and Oral Iron Sulfate for Anemic Patients with Inflammatory Bowel Disease in Korea

Han YM, Yoon H, Shin CM, Koh SJ, Im JP, Kim BG, Kim JS, Jung HC

BACKGROUND/AIMS: The optimal route for iron administration in anemic patients with inflammatory bowel disease (IBD) has not been determined. The aim of this study was to compare the efficacies of...
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Recent advances in the imaging of hepatocellular carcinoma

You MW, Kim SY, Kim KW, Lee SJ, Shin YM, Kim JH, Lee MG

The role of imaging is crucial for the surveillance, diagnosis, staging and treatment monitoring of hepatocellular carcinoma (HCC). Over the past few years, considerable technical advances were made in imaging...
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Trastuzumab-Conjugated Liposome-Coated Fluorescent Magnetic Nanoparticles to Target Breast Cancer

Jang M, Yoon YI, Kwon YS, Yoon TJ, Lee HJ, Hwang SI, Yun BL, Kim SM

OBJECTIVE: To synthesize mesoporous silica-core-shell magnetic nanoparticles (MNPs) encapsulated by liposomes (Lipo [MNP@m-SiO2]) in order to enhance their stability, allow them to be used in any buffer solution, and to...
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Radiofrequency ablation of very-early-stage hepatocellular carcinoma inconspicuous on fusion imaging with B-mode US: value of fusion imaging with contrast-enhanced US

Min JH, Lim HK, Lim S, Kang TW, Song KD, Choi SY, Rhim H, Lee MW

BACKGROUND/AIMS: To determine the value of fusion imaging with contrast-enhanced ultrasonography (CEUS) and computed tomography (CT)/magnetic resonance (MR) images for percutaneous radiofrequency ablation (RFA) of very-early-stage hepatocellular carcinomas (HCCs) that...
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Distribution and accumulation of Cy5.5-labeled thermally cross-linked superparamagnetic iron oxide nanoparticles in the tissues of ICR mice

Hue JJ, Lee HJ, Jon S, Nam SY, Yun YW, Kim JS, Lee BJ

Free Cy5.5 dye and Cy5.5-labeled thermally cross-linked superparamagnetic iron oxide nanoparticles (TCL-SPION) have been routinely used for in vivo optical imaging. However, there is little information about the distribution and...
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Serial MR Imaging of Magnetically Labeled Humen Umbilical Vein Endothelial Cells in Acute Renal Failure Rat Model

Lee SJ, Lee SY, Kang KP, Kim W, Park SK

PURPOSE: To evaluate the usefulness of in vivo magnetic resonance (MR) imaging for tracking intravenously injected superparamagnetic iron oxide (SPIO)-labeled human umbilical vein endothelial cells (HUVECs) in an acute renal...
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Intravenous Iron Sucrose for Three Children with Iron Deficiency Anemia Failing to Respond to Oral Iron Therapy

Lee JW, Kim DH, Lee JE, Kim SK

  • KMID: 2049292
  • Clin Pediatr Hematol Oncol.
  • 2013 Apr;20(1):51-54.
Iron deficiency anemia is still a common pediatric hematologic disease in the world. First line treatment for iron deficiency anemia is oral iron supplementation. However, some children need parenteral iron...
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Comparison of Superparamagnetic Iron Oxide Labeling Efficiency between Poly-L-Lysine and Protamine Sulfate for Human Mesenchymal Stem Cells: Quantitative Analysis Using Multi-Echo T2* Magnetic Resonance Imaging

Suh JY, Lee JH, Lee CK, Shin JH, Choi CG, Kim JK

PURPOSE: To quantify in vitro labeling efficiency of protamine sulfate (PS) and poly-L-lysine (PLL) for labeling of human mesenchymal stem cells (hMSCs) with superparamagnetic iron oxide (SPIO) using multi-echo T2*...
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Diffusion-Weighted MR Imaging before and after Contrast Enhancement with Superparamagnetic Iron Oxide for Assessment of Hepatic Metastasis

Kim H, Yu JS, Kim DJ, Chung JJ, Kim JH, Kim KW

PURPOSE: The purpose of our study was to validate diffusion-weighted MRI (DWI) before and after superparamagnetic iron oxide (SPIO) injection for assessment of hepatic metastases. MATERIALS AND METHODS: Eighty-six hepatic metastases...
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Evaluation of Optimal Combination of Commercially Available Superparamagnetic Iron Oxide Nanoparticles and Transfection Agents for Labelling of Human Mesenchymal Stem Cells

Kim SH, Oh SN, Park YH, Kang WK, Ahn KJ, Chung SK

PURPOSE: To determine the optimal combination of commercially available superparamagnetic iron oxide (SPIO) nanoparticles with transfection agents (TA). MATERIALS AND METHODS: Protamine sulfate (Pro) and poly-L-lysin (PLL) were incubated with ferumoxide...
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Iron deficiency anemia in childhood

Yoon HS

  • KMID: 2341915
  • J Korean Med Assoc.
  • 2011 Jul;54(7):725-729.
Iron deficiency anemia (IDA) frequently occurs in infants and adolescents. IDA is the result of an interplay between increased host requirements, limited external supply, and increased blood loss. In outpatient...
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A Case of Pulmonary Siderosis Mimicking Metastatic Lung Cancer

Koo SM, Park SW, Park JS, Lee JH, Jang AS, Kim DJ, Park CS, Paik SH, Koh ES

  • KMID: 2319468
  • Tuberc Respir Dis.
  • 2011 Jan;70(1):58-62.
Pulmonary siderosis is a pneumoconiosis caused by chronic iron inhalation. A diagnosis of pulmonary siderosis is based on a patient history of iron inhalation, on chest radiographic findings, and on...
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Hepatic Angiomyolipoma: Dual-Contrast MRI Findings Using Superparamagnetic Iron Oxide (SPIO) and Gadolinium Agents

Kim MU, Kim SH, Kim HC, Lee JY, Kim MA, Han JK, Choi BI

  • KMID: 2344972
  • J Korean Soc Radiol.
  • 2010 Dec;63(6):537-546.
PURPOSE: To analyze imaging findings of hepatic angiomyolipomas (AMLs) on dual-contrast MRI using superparamagnetic iron oxide (SPIO) and gadolinium (Gd) agents. MATERIALS AND METHODS: Five histopathologically-proven hepatic AMLs were enrolled in...
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Monitoring Transplanted Human Mesenchymal Stem Cells in the Penile Cavernosal Tissues of Streptozotocin-induced Diabetic Rats Using Molecular Magnetic Resonance Imaging

Song YS, Yoon JH, Doo SW, Yang WJ, Kim JH, Choi DH, Kim SJ, Chung HJ, Won JH

  • KMID: 2298751
  • Korean J Androl.
  • 2010 Dec;28(3):163-168.
PURPOSE: A molecular magnetic resonance (MR) imaging technique using superparamagnetic iron oxide (SPIO) nanocrystals was developed for monitoring stem cells noninvasively. This study was performed to investigate whether the presence...
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Postoperative High-Dose Intravenous Iron Sucrose with Low Dose Erythropoietin Therapy after Total Hip Replacement

Yoon J, Kim S, Lee SC, Lim H

Erythropoietin combined with parenteral iron sucrose therapy is an alternative to blood transfusion in anemic patients. It was shown to be effective in surgical patients in several previous studies when...
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The Effects of Preoperatively Administering Parenteral Iron Sucrose in Patients Who Are Undergoing Total Knee Arthroplasty

Bae KC, Cho CH, Lee KJ, Lee SY

  • KMID: 2064549
  • J Korean Knee Soc.
  • 2010 Jun;22(2):124-129.
PURPOSE: The purpose of this study was to evaluate the efficacy of preoperative parenteral iron sucrose therapy in patients with postoperative anemia following total knee arthroplasty. MATERIALS AND METHODS: We retrospectively...
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In vivo Tracking of Mesenchymal Stem Cells Labeled with a Novel Chitosan-coated Superparamagnetic Iron Oxide Nanoparticles using 3.0T MRI

Reddy AM, Kwak BK, Shim HJ, Ahn C, Lee HS, Suh YJ, Park ES

This study aimed to characterize and MRI track the mesenchymal stem cells labeled with chitosan-coated superparamagnetic iron oxide (Chitosan-SPIO). Chitosan-SPIO was synthesized from a mixture of FeCl2 and FeCl3. The...
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Dual-Modal Nanoprobes for Imaging of Mesenchymal Stem Cell Transplant by MRI and Fluorescence Imaging

Sung CK, Hong KA, Lin S, Lee Y, Cha J, Lee JK, Hong CP, Han BS, Jung SI, Kim SH, Yoon KS

OBJECTIVE: To determine the feasibility of labeling human mesenchymal stem cells (hMSCs) with bifunctional nanoparticles and assessing their potential as imaging probes in the monitoring of hMSC transplantation. MATERIALS AND...
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Intravenous Iron Supplementation in Korean Children on Chronic Dialysis

Cho HY, Hahn H, Ha IS, Cheong HI, Choi Y

  • KMID: 2322105
  • J Korean Soc Pediatr Nephrol.
  • 2009 Oct;13(2):197-206.
PURPOSE: Limited information is available on experiences of intravenous iron treatment in children. In this study, iron sucrose was administered intravenously to determine its effect, the factors predicting outcome, and...
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