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Role of Fecal Calprotectin in Differentiating between Hirschsprung's Disease and Functional Constipation

Mahjoub FE, Zahedi N, Ashjai B, Haghi Ashtiani MT, Farahmand , Monajemzadeh M, Kashi L, Iranikhah

BACKGROUND/AIMS: Calprotectin is a 36.5 kD calcium and zinc binding protein in the S100 protein family. Fecal calprotectin levels are elevated in patients with inflammatory bowel disease and some other...
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Irritable Bowel Syndrome, Particularly the Constipation-Predominant Form, Involves an Increase in Methanobrevibacter smithii, Which Is Associated with Higher Methane Production

Ghoshal U, Shukla R, Srivastava D, Ghoshal UC

BACKGROUND/AIMS: Because Methanobrevibacter smithii produces methane, delaying gut transit, we evaluated M. smithii loads in irritable bowel syndrome (IBS) patients and healthy controls (HC). METHODS: Quantitative real-time polymerase chain reaction for...
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Identification of CD44 splice variant in Korean colorectal cancers and cell lines

Suh SI, Baek WK, Park JW, Bae OS, Suh MH, Choe BK

CD44 is a glycoprotein expressed in a wide variety of cell types. Recently expression of some alternatively-spliced variants of CD44 transcripts (CD44v) has been suggested to play a potential role...
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Bile Acid Diarrhea: Prevalence, Pathogenesis, and Therapy

Camilleri

Bile acid diarrhea (BAD) is usually seen in patients with ileal Crohn's disease or ileal resection. However, 25% to 50% of patients with functional diarrhea or diarrhea-predominant irritable bowel syndrome...
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