- Synthesis of recombinant blood coagulation factor VIII (FVIII) heavy and light chains and reconstitution of active form of FVIII
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Oh SH, Lee MY, Song DW
- KMID: 1029938
- Exp Mol Med.
- 1999 Jun;31(2):95-100.
FVIII is synthesized as a single chain precursor of approximately 280 kD with the domain structure of A1-A2-B-A3-C1-C2 and it circulates as a series of metal ion-linked heterodimers that result from cleavages... -
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- Delivery of Factor VIII Gene into Skeletal Muscle Cells Using Lentiviral Vector
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Jeon HJ, Oh TK, Kim OH, Kim ST
- KMID: 1779606
- Yonsei Med J.
- 2010 Jan;51(1):52-57.
- doi: 10.3349/ymj.2010.51.1.52
PURPOSE: This study was designed to investigate whether transduction of lentiviral vectors (LV) carrying human coagulation factor VIII (hFVIII) cDNA into skeletal muscle could increase circulating hFVIII concentrations. MATERIALS AND... -
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