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Synthesis of recombinant blood coagulation factor VIII (FVIII) heavy and light chains and reconstitution of active form of FVIII

Oh SH, Lee MY, Song DW

  • KMID: 1029938
  • Exp Mol Med.
  • 1999 Jun;31(2):95-100.
FVIII is synthesized as a single chain precursor of approximately 280 kD with the domain structure of A1-A2-B-A3-C1-C2 and it circulates as a series of metal ion-linked heterodimers that result from cleavages...
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A pathologic study of abdominal lymphangiomas

Chung JH, Suh YL, Park IA, Jang JJ, Chi JG, Kim YI, Kim WH

Abdominal lymphangiomas are uncommon angiomatous tumor occurring mainly in childhood. This is a retrospective clinicopathologic study of 17 cases of abdominal lymphangioma. The patients included are five children and 12...
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Expression and characterization of a mutant recombinant blood coagulation factor VIII (rFVIII (m)).

Oh SH, Cho SY, Jin HS, Jeong DL, Jung SG, Oh KH

  • KMID: 1380231
  • Exp Mol Med.
  • 2002 Jul;34(3):233-238.
In an earlier study, a site directed mutant rFVIII (rFVIII(m), Arg(336) -> Gln(336)) expressed in baculovirus-insect cell (Sf9) system was found to sustain high level activity during incubation at 37...
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