- Induction of tissue inhibitor of matrix metalloproteinase-2 by cholesterol depletion leads to the conversion of proMMP-2 into active MMP-2 in human dermal fibroblasts
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Kim S, Oh JH, Lee Y, Lee J, Cho KH, Chung JH
- KMID: 946668
- Exp Mol Med.
- 2010 Jan;42(1):38-46.
- doi: 10.3858/emm.2010.42.1.004
Cholesterol is one of major components of cell membrane and plays a role in vesicular trafficking and cellular signaling. We investigated the effects of cholesterol on matrix metalloproteinase-2 (MMP-2) activation... -
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- C-Jun NH2-Terminal Kinase Contributes to Dexmedetomidine-Induced Contraction in Isolated Rat Aortic Smooth Muscle
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Ok SH, Jeong YS, Kim JG, Lee SM, Sung HJ, Kim HJ, Chang KC, Kwon SC, Sohn JT
- KMID: 1777013
- Yonsei Med J.
- 2011 May;52(3):420-428.
- doi: 10.3349/ymj.2011.52.3.420
PURPOSE: Dexmedetomidine, a full agonist of alpha2B-adrenoceptors, is used for analgesia and sedation in the intensive care units. Dexmedetomidine produces an initial transient hypertension due to the activation of post-junctional... -
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