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Simultaneous Cellular Imaging, Electrical Recording and Stimulation of Hippocampal Activity in Freely Behaving Mice

Kim CY, Kim SJ, Kloosterman F

  • KMID: 2531124
  • Exp Neurobiol.
  • 2022 Jun;31(3):208-220.
  • doi: 10.5607/en22011
Hippocampal sharp-wave ripple activity (SWRs) and the associated replay of neural activity patterns are well-known for their role in memory consolidation. This activity has been studied using electrophysiological approaches, as...
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The Change in Circadian Rhythms in P301S Transgenic Mice is Linked to Variability in Hsp70-related Tau Disaggregation

Han SM, Jang YJ, Kim EY, Park SA

  • KMID: 2531123
  • Exp Neurobiol.
  • 2022 Jun;31(3):196-207.
  • doi: 10.5607/en22019
Circadian disruption often involves a neurodegenerative disorder, such as Alzheimer’s disease or frontotemporal dementia, which are characterized by intraneuronal tau accumulations. The altered sleep pattern and diurnal rhythms in these...
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Astrocyte-targeted Overproduction of IL-10 Reduces Neurodegeneration after TBI

Shanaki-Barvasad M, Almolda B, González B, Castellano B

  • KMID: 2531121
  • Exp Neurobiol.
  • 2022 Jun;31(3):173-195.
  • doi: 10.5607/en21035
Traumatic brain injury is the greatest cause of disability and death in young adults in the developed world. The outcome for a TBI patient is determined by the severity of...
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Generation of Astrocyte-Specific MAOB Conditional Knockout Mouse with Minimal Tonic GABA Inhibition

Lee JM, Sa M, An H, Kim JMJ, Kwon J, Yoon BE, Lee CJ

  • KMID: 2531119
  • Exp Neurobiol.
  • 2022 Jun;31(3):158-172.
  • doi: 10.5607/en22016
Monoamine oxidase B (MAOB) is a key enzyme for GABA production in astrocytes in several brain regions. To date, the role of astrocytic MAOB has been studied in MAOB null...
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Unaltered Tonic Inhibition in the Arcuate Nucleus of Diet-induced Obese Mice

Sa M, Lee JM, Park MG, Lim J, Joseph Kim JM, Koh W, Yoon BE, Lee CJ

  • KMID: 2531118
  • Exp Neurobiol.
  • 2022 Jun;31(3):147-157.
  • doi: 10.5607/en22014
The principal inhibitory transmitter, γ-aminobutyric acid (GABA), is critical for maintaining hypothalamic homeostasis and released from neurons phasically, as well as from astrocytes tonically. Although astrocytes in the arcuate nucleus...
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Cranial and Spinal Window Preparation for in vivo Optical Neuroimaging in Rodents and Related Experimental Techniques

Yeon C, Im JM, Kim M, Kim YR, Chung E

  • KMID: 2531117
  • Exp Neurobiol.
  • 2022 Jun;31(3):131-146.
  • doi: 10.5607/en22015
Optical neuroimaging provides an effective neuroscience tool for multi-scale investigation of the neural structures and functions, ranging from molecular, cellular activities to the inter-regional connectivity assessment. Amongst experimental preparations, the...
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