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Alendronate Enhances Functional Recovery after Spinal Cord Injury

Choi Y, Shin T

Spinal cord injury is a destructive disease characterized by motor/sensory dysfunction and severe inflammation. Alendronate is an anti-inflammatory molecule and may therefore be of benefit in the treatment of the...
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Diffusion MRI Connections in the Octopus Brain

Jacobs RE

Using high angle resolution diffusion magnetic resonance imaging (HARDI) with fiber tractography analysis we map out a meso-scale connectome of the Octopus bimaculoides brain. The brain of this cephalopod has...
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Conformation-specific Antibodies Targeting Aggregated Forms of α-synuclein Block the Propagation of Synucleinopathy

Choi M, Kim Tk, Ahn J, Lee JS, Jung BC, An S, Kim D, Lee MJ, Mook-Jung I, Lee SH, Lee SJ

Abnormal aggregation of α-synuclein is a key element in the pathogenesis of several neurodegenerative diseases, including Parkinson’s disease (PD), dementia with Lewy bodies, and multiple system atrophy. α-synuclein aggregation spreads...
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Interleukin 13 on Microglia is Neurotoxic in Lipopolysaccharide-injected Striatum in vivo

Hong AR, Jang JG, Chung YC, Won SY, Jin BK

To explore the potential function of interleukin-13 (IL-13), lipopolysaccharide (LPS) or PBS as a control was unilaterally microinjected into striatum of rat brain. Seven days after LPS injection, there was...
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Invertebrate Model Organisms as a Platform to Investigate Rare Human Neurological Diseases

Lee JH

Patients suffering from rare human diseases often go through a painful journey for finding a definite molecular diagnosis prerequisite of appropriate cures. With a novel variant isolated from a single...
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