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Deletion of Phospholipase C β1 in the Thalamic Reticular Nucleus Induces Absence Seizures

  • KMID: 2530369
  • Exp Neurobiol.
  • 2022 Apr;31(2):116-130.
  • doi: 10.5607/en22007
Absence seizures are caused by abnormal synchronized oscillations in the thalamocortical (TC) circuit, which result in widespread spike-and-wave discharges (SWDs) on electroencephalography (EEG) as well as impairment of consciousness. Thalamic...
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The Indirect Effect of Prefrontal Gray Matter Volume on Suicide Attempts among Individuals with Major Depressive Disorder

Kang J, Kim A, Kang Y, Han KM, Ham BJ

Trait impulsivity is a known risk factor for suicidality, and the prefrontal cortex plays a key role in impulsivity and its regulation. However, the relationship between trait impulsivity, neural basis,...
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Time Course of Remote Neuropathology Following Diffuse Traumatic Brain Injury in the Male Rat

Giordano KR, Law LM, Henderson J, Rowe RK, Lifshitz J

  • KMID: 2530368
  • Exp Neurobiol.
  • 2022 Apr;31(2):105-115.
  • doi: 10.5607/en21027
Traumatic brain injury (TBI) can affect different regions throughout the brain. Regions near the site of impact are the most vulnerable to injury. However, damage to distal regions occurs. We...
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Physiological Roles of Monomeric Amyloid-β and Implications for Alzheimer’s Disease Therapeutics

Jeong H, Shin H, Hong S, Kim Y

Alzheimer’s disease (AD) progressively inflicts impairment of synaptic functions with notable deposition of amyloid-β (Aβ) as senile plaques within the extracellular space of the brain. Accordingly, therapeutic directions for AD...
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Neonatal Mice Spinal Cord Interneurons Send Axons through the Dorsal Roots

Osuna-Carrasco LP, Osuna-Carrasco LP, Dueñas-Jiménez SH, Toro-Castillo C, Torre BDl, Aguilar-García I, Alpirez J, Castillo L, Dueñas-Jiménez JM

Spontaneous interneuron activity plays a critical role in developing neuronal networks. Discharges conducted antidromically along the dorsal root (DR) precede those from the ventral root’s (VR) motoneurons. This work studied...
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