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Pim-1 Protects Retinal Ganglion Cells by Enhancing Their Regenerative Ability Following Optic Nerve Crush

Zhang S, Shuai L, Wang D, Huang T, Yang S, Miao M, Liu F, Xu J

  • KMID: 2503984
  • Exp Neurobiol.
  • 2020 Jun;29(3):249-272.
  • doi: 10.5607/en20019
Provirus integration site Moloney murine leukemia virus (Pim-1) is a proto-oncogene reported to be associated with cell proliferation, differentiation and survival. This study was to explore the neuroprotective role of...
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Absence of Glia Maturation Factor Protects from Axonal Injury and Motor Behavioral Impairments after Traumatic Brain Injury

Selvakumar GP, Ahmed ME, Iyer SS, Thangavel R, Kempuraj D, Raikwar SP, Bazley K, Wu K, Khan A, Kukulka K, Bussinger B, Zaheer S, Burton C, James D, Zaheer A

  • KMID: 2503983
  • Exp Neurobiol.
  • 2020 Jun;29(3):230-248.
  • doi: 10.5607/en20017
Traumatic brain injury (TBI) causes disability and death, accelerating the progression towards Alzheimer’s disease and Parkinson’s disease (PD). TBI causes serious motor and cognitive impairments, as seen in PD that...
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Labeling Dual Presynaptic Inputs using cFork Anterograde Tracing System

Oh JY, Han JH, Lee H, Han YE, Rah JC, Park H

  • KMID: 2503982
  • Exp Neurobiol.
  • 2020 Jun;29(3):219-229.
  • doi: 10.5607/en20006
Understanding brain function-related neural circuit connectivity is essential for investigating how cognitive functions are decoded in neural circuits. Trans-synaptic viral vectors are useful for identifying neural synaptic connectivity because of...
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Death-associated Protein Kinase 1 Phosphorylates α-Synuclein at Ser129 and Exacerbates Rotenone-induced Toxic Aggregation of α-Synuclein in Dopaminergic SH-SY5Y Cells

Shin WH, Chung KC

  • KMID: 2503981
  • Exp Neurobiol.
  • 2020 Jun;29(3):207-218.
  • doi: 10.5607/en20014
The formation of Lewy bodies (LBs), intracellular filamentous inclusions, is one of the hallmarks of Parkinson's disease (PD). α-Synuclein is the main component of LBs and its abnormal accumulation contributes...
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ERK Regulates NeuroD1-mediated Neurite Outgrowth via Proteasomal Degradation

Lee Ty, Cho IS, Bashyal N, Naya FJ, Tsai MJ, Yoon JS, Choi JM, Park CH, Kim SS, Suh-Kim H

  • KMID: 2503980
  • Exp Neurobiol.
  • 2020 Jun;29(3):189-206.
  • doi: 10.5607/en20021
Neurogenic differentiation 1 (NeuroD1) is a class B basic helix-loop-helix (bHLH) transcription factor and regulates differentiation and survival of neuronal and endocrine cells by means of several protein kinases, including...
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Gene Therapy Options as New Treatment for Inherited Peripheral Neuropathy

Thenmozhi R, Lee JS, Park NY, Choi BO, Hong YB

  • KMID: 2503979
  • Exp Neurobiol.
  • 2020 Jun;29(3):177-188.
  • doi: 10.5607/en20004
Inherited peripheral neuropathy (IPN) is caused by heterogeneous genetic mutations in more than 100 genes. So far, several treatment options for IPN have been developed and clinically evaluated using small...
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