- Cortical Axonal Secretion of BDNF in the Striatum Is Disrupted in the Mutant-huntingtin Knock-in Mouse Model of Huntington's Disease
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Park H
- KMID: 2416249
- Exp Neurobiol.
- 2018 Jun;27(3):217-225.
- doi: 10.5607/en.2018.27.3.217
Deficient BDNF signaling is known to be involved in neurodegenerative diseases such as Huntington's disease (HD). Mutant huntingtin (mhtt)-mediated disruption of either BDNF transcription or transport is thought to be... -
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- Blue-on-Green Flash Induces Maximal Photopic Negative Response and Oscillatory Potential and Serves as a Diagnostic Marker for Glaucoma in Rat Retina
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Park SJ, Paik SS, Lee JY, Oh SJ, Kim IB
- KMID: 2416248
- Exp Neurobiol.
- 2018 Jun;27(3):210-216.
- doi: 10.5607/en.2018.27.3.210
The purpose of this study was to investigate the application of various electroretinography (ERG) to the diagnosis of inner retinal dysfunction induced by mild intraocular pressure (IOP) elevation in a... -
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- Desynchronization of Theta Oscillations in Prefrontal Cortex during Self-stimulation of the Medial Forebrain Bundles in Mice
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Hwang E, Lee H, Choi JH
- KMID: 2416245
- Exp Neurobiol.
- 2018 Jun;27(3):181-188.
- doi: 10.5607/en.2018.27.3.181
Stimulation of the medial forebrain bundle (MFB) can reinforce intracranial self-stimulation (ICSS) in rodents (i.e., reward-seeking behavior). The MFB stimulation produces a highly reliable behavioral output that enabled a clear... -
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- The Emerging Concept of Intrinsic Plasticity: Activity-dependent Modulation of Intrinsic Excitability in Cerebellar Purkinje Cells and Motor Learning
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Shim HG, Lee YS, Kim SJ
- KMID: 2416242
- Exp Neurobiol.
- 2018 Jun;27(3):139-154.
- doi: 10.5607/en.2018.27.3.139
What is memory? How does the brain process the sensory information and modify an organism's behavior? Many neuroscientists have focused on the activity- and experience-dependent modifications of synaptic functions in... -
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- Leucine-rich G Protein-coupled Receptor-5 Is Significantly Increased in the Aqueous Humor of Human Eye with Proliferative Diabetic Retinopathy
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Hong EH, Hwang M, Shin YU, Park HH, Koh SH, Cho H
- KMID: 2416251
- Exp Neurobiol.
- 2018 Jun;27(3):238-244.
- doi: 10.5607/en.2018.27.3.238
Leucine-rich G protein-coupled receptor-5 (LGR5) is known to be a stem cell marker in many organs. LGR5 may have important roles in proliferative diabetic retinopathy (PDR) because LGR5 potentiate the... -
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- Morin Prevents Granule Cell Dispersion and Neurotoxicity via Suppression of mTORC1 in a Kainic Acid-induced Seizure Model
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Lee JM, Hong J, Moon GJ, Jung UJ, Won SY, Kim SR
- KMID: 2416250
- Exp Neurobiol.
- 2018 Jun;27(3):226-237.
- doi: 10.5607/en.2018.27.3.226
An abnormal reorganization of the dentate gyrus and neurotoxic events are important phenotypes in the hippocampus of patients with temporal lobe epilepsy (TLE). The effects of morin, a bioflavonoid constituent... -
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- Radix Polygalae Extract Attenuates PTSD-like Symptoms in a Mouse Model of Single Prolonged Stress and Conditioned Fear Possibly by Reversing BAG1
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Shin JY, Shin JW, Ha SK, Kim Y, Swanberg K, Lee S, Kim TW, Maeng S
- KMID: 2416247
- Exp Neurobiol.
- 2018 Jun;27(3):200-209.
- doi: 10.5607/en.2018.27.3.200
Radix Polygalae (RP) has been used to relieve psychological stress in traditional oriental medicine. Recently, cell protective, antiamnestic and antidepressant-like effects were disclosed but the possible application of RP to... -
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- Astrocytic proBDNF and Tonic GABA Distinguish Active versus Reactive Astrocytes in Hippocampus
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Chun H, An H, Lim J, Woo J, Lee J, Ryu H, Lee CJ
- KMID: 2416243
- Exp Neurobiol.
- 2018 Jun;27(3):155-170.
- doi: 10.5607/en.2018.27.3.155
Astrocytes are the most abundant cell type in the brain and they make close contacts with neurons and blood vessels. They respond dynamically to various environmental stimuli and change their... -
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- LRRK2 Kinase Activity Induces Mitochondrial Fission in Microglia via Drp1 and Modulates Neuroinflammation
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Ho DH, Je AR, Lee H, Son I, Kweon HS, Kim HG, Seol W
- KMID: 2416244
- Exp Neurobiol.
- 2018 Jun;27(3):171-180.
- doi: 10.5607/en.2018.27.3.171
Leucine-rich repeat kinase 2 (LRRK2) mutations are the most common genetic cause of Parkinson's disease (PD). LRRK2 contains a functional kinase domain and G2019S, the most prevalent LRRK2 pathogenic mutation,... -
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- Fractionated Gamma Knife Radiosurgery as Initial Treatment for Large Skull Base Meningioma
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Park HR, Lee JM, Park KW, Kim JH, Jeong SS, Kim JW, Chung HT, Kim DG, Paek SH
- KMID: 2416252
- Exp Neurobiol.
- 2018 Jun;27(3):245-255.
- doi: 10.5607/en.2018.27.3.245
We present our experience on the hypofractionated Gamma Knife radiosurgery (FGKS) for large skull base meningioma as an initial treatment. We retrospectively reviewed 23 patients with large skull base meningioma... -
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- Antidepressant-like Effects of p-Coumaric Acid on LPS-induced Depressive and Inflammatory Changes in Rats
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Lee S, Kim HB, Hwang ES, Kim ES, Kim SS, Jeon TD, Song MC, Lee JS, Chung MC, Maeng S, Park JH
- KMID: 2416246
- Exp Neurobiol.
- 2018 Jun;27(3):189-199.
- doi: 10.5607/en.2018.27.3.189
Depression causes mental and physical changes which affect quality of life. It is estimated to become the second most prevalent disease, but despite its commonness, the pathophysiology of depression remains... -
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