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Bilateral Adduction Palsy in a Patient with Myotonic Dystrophy Type 1

Kim HJ, Oh JH, Kang SY

Myotonic dystrophy type 1 (DM1) is caused by CTG repeat expansion in the DMPK gene in chromosome 19q13.3. External ophthalmoplegia is a rare manifestation in DM1. We report a DM1...
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Toxocara canis-Associated Myelitis with Eosinophilic Pneumonia

Park KH, Kim YS, Kim SK, Choi NC, Kwon OY, Lim B, Park KJ

The existence of Toxocara canis-specific antibodies has recently been reported in patients with atopic myelitis. Here, we report the case of a 35-year-old male patient admitted with a chief complaint...
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Cerebral Hemodynamics and Vascular Reactivity in Mild and Severe Ischemic Rodent Middle Cerebral Artery Occlusion Stroke Models

Sim J, Jo A, Kang BM, Lee S, Bang OY, Heo C, Jhon GJ, Lee Y, Suh M

Ischemia can cause decreased cerebral neurovascular coupling, leading to a failure in the autoregulation of cerebral blood flow. This study aims to investigate the effect of varying degrees of ischemia...
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Neuronal Expression and Cell-Type-Specific Gene-Silencing of Best1 in Thalamic Reticular Nucleus Neurons Using pSico-Red System

Jung JY, Lee SE, Hwang EM, Lee CJ

Assessing the cell-type expression pattern of a certain gene can be achieved by using cell-type-specific gene manipulation. Recently, cre-recombinase-dependent gene-silencing tool, pSico has become popular in neuroscientific research. However, pSico...
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Non-cell-autonomous Neurotoxicity of α-synuclein Through Microglial Toll-like Receptor 2

Kim C, Lee HJ, Masliah E, Lee SJ

Synucleinopathies are a collection of neurological diseases that are characterized by deposition of α-synuclein aggregates in neurons and glia. These diseases include Parkinson's disease (PD), dementia with Lewy bodies, and...
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Adult Neurogenesis and Gliogenesis: Possible Mechanisms for Neurorestoration

Rusznák Z, Henskens W, Schofield , Kim WS, Fu Y

The subgranular zone (SGZ) and subventricular zone (SVZ) are developmental remnants of the germinal regions of the brain, hence they retain the ability to generate neuronal progenitor cells in adult...
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