Skip Navigation
Skip to contents
Filter

ARTICLE TYPE

PUBLICATION DATE

14 results
Display

Microbiota in T-cell homeostasis and inflammatory diseases

Lee N, Kim WU

The etiology of disease pathogenesis can be largely explained by genetic variations and several types of environmental factors. In genetically disease-susceptible individuals, subsequent environmental triggers may induce disease development. The...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The interplay between host immune cells and gut microbiota in chronic inflammatory diseases

Kim D, Zeng MY, Núñez G

Many benefits provided by the gut microbiota to the host rely on its intricate interactions with host cells. Perturbations of the gut microbiota, termed gut dysbiosis, affect the interplay between...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Roles of intestinal epithelial cells in the maintenance of gut homeostasis

Okumura R, Takeda K

The intestine is a unique organ inhabited by a tremendous number of microorganisms. Intestinal epithelial cells greatly contribute to the maintenance of the symbiotic relationship between gut microbiota and the...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Dysregulation of gut microbiota and chronic inflammatory disease: from epithelial defense to host immunity

Koh JH, Kim WU

No abstract available.
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
A FKBP5 mutation is associated with Paget's disease of bone and enhances osteoclastogenesis

Lu B, Jiao Y, Wang Y, Dong J, Wei M, Cui B, Sun Y, Wang L, Zhang B, Chen Z, Zhao Y

Paget's disease of bone (PDB) is a common metabolic bone disease that is characterized by aberrant focal bone remodeling, which is caused by excessive osteoclastic bone resorption followed by disorganized...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Aberrant epigenetic regulation of GABRP associates with aggressive phenotype of ovarian cancer

Sung HY, Yang SD, Ju W, Ahn JH

Metastasis is a major cause of therapeutic failure in ovarian cancer. To elucidate molecular mechanisms of ovarian cancer metastasis, we previously established a metastatic xenograft mouse model using human ovarian...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Role of carbonic anhydrases in skin wound healing

Barker H, Aaltonen M, Pan P, Vähätupa M, Kaipiainen P, May U, Prince S, Uusitalo-Järvinen H, Waheed A, Pastoreková S, Sly WS, Parkkila S, Järvinen

Skin wound closure occurs when keratinocytes migrate from the edge of the wound and re-epithelialize the epidermis. Their migration takes place primarily before any vascularization is established, that is, under...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Transcriptome analyses of chronic traumatic encephalopathy show alterations in protein phosphatase expression associated with tauopathy

Seo JS, Lee S, Shin JY, Hwang YJ, Cho H, Yoo SK, Kim Y, Lim S, Kim YK, Hwang EM, Kim SH, Kim CH, Hyeon SJ, Yun JY, Kim J, Kim Y, Alvarez VE, Stein TD, Lee J, Kim DJ, Kim JI, Kowall NW, Ryu H, McKee AC

Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative disorder that is associated with repetitive head injury and has distinctive neuropathological features that differentiate this disease from other neurodegenerative diseases. Intraneuronal...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Lentivirus-mediated microRNA-124 gene-modified bone marrow mesenchymal stem cell transplantation promotes the repair of spinal cord injury in rats

Song JL, Zheng W, Chen W, Qian Y, Ouyang YM, Fan CY

Our study aims to explore the effects of lentivirus-mediated microRNA-124 (miR-124) gene-modified bone marrow mesenchymal stem cell (BMSC) transplantation on the repair of spinal cord injury (SCI) in rats. BMSCs...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Engulfment signals and the phagocytic machinery for apoptotic cell clearance

Park SY, Kim IS

The clearance of apoptotic cells is an essential process for tissue homeostasis. To this end, cells undergoing apoptosis must display engulfment signals, such as ‘find-me' and ‘eat-me' signals. Engulfment signals...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Helicobacter pylori-derived extracellular vesicles increased in the gastric juices of gastric adenocarcinoma patients and induced inflammation mainly via specific targeting of gastric epithelial cells

Choi HI, Choi JP, Seo J, Kim BJ, Rho M, Han JK, Kim JG

Evidence indicates that Helicobacter pylori is the causative agent of chronic gastritis and perhaps gastric malignancy. Extracellular vesicles (EVs) play an important role in the evolutional process of malignancy due...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Upregulation and biological function of transmembrane protein 119 in osteosarcoma

Jiang ZH, Peng J, Yang HL, Fu XL, Wang JZ, Liu L, Jiang JN, Tan YF, Ge ZJ

Osteosarcoma is suggested to be caused by genetic and molecular alterations that disrupt osteoblast differentiation. Recent studies have reported that transmembrane protein 119 (TMEM119) contributes to osteoblast differentiation and bone...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Bone-forming peptide-2 derived from BMP-7 enhances osteoblast differentiation from multipotent bone marrow stromal cells and bone formation

Kim HK, Lee JS, Kim JH, Seon JK, Park KS, Jeong MH, Yoon TR

Strategies for efficient osteogenic differentiation and bone formation from stem cells would have clinical applications in treating nonunion fracture healing. Many researchers have attempted to develop adjuvants as specific stimulators...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
microRNA-200a-3p increases 5-fluorouracil resistance by regulating dual specificity phosphatase 6 expression

Lee H, Kim C, Kang H, Tak H, Ahn S, Yoon SK, Kuh HJ, Kim W, Lee EK

Acquisition of resistance to anti-cancer drugs is a significant obstacle to effective cancer treatment. Although several efforts have been made to overcome drug resistance in cancer cells, the detailed mechanisms...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2020 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr