- Aptamer–nanoparticle complexes as powerful diagnostic and therapeutic tools
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Jo H, Ban C
- KMID: 2361517
- Exp Mol Med.
- 2016 May;48(5):e230.
- doi: 10.1038/emm.2016.44
Correct diagnosis and successful therapy are extremely important to enjoy a healthy life when suffering from a disease. To achieve these aims, various cutting-edge technologies have been designed and fabricated... -
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- F-box only protein 9 is an E3 ubiquitin ligase of PPARγ
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Lee KW, Kwak SH, Koo YD, Cho YK, Lee HM, Jung HS, Cho YM, Park YJ, Chung SS, Park KS
- KMID: 2361521
- Exp Mol Med.
- 2016 May;48(5):e234.
- doi: 10.1038/emm.2016.31
Peroxisome proliferator-activated receptor gamma (PPARγ) is a critical regulator of carbohydrate and lipid metabolism, adipocyte differentiation and inflammatory response. Post-translational modification of PPARγ and its degradation involve several pathways, including... -
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- GLCCI1 is a novel component associated with the PI3K signaling pathway in podocyte foot processes
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Kim SH, Kim HJ, Kim CW
- KMID: 2361520
- Exp Mol Med.
- 2016 May;48(5):e233.
- doi: 10.1038/emm.2016.28
Podocyte foot processes are interdigitated to form the slit diaphragm and are crucial for the glomerular filtration barrier. Glucocorticoid-induced transcript 1 (GLCCI1) is transcriptionally regulated, but its signaling pathway in... -
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- Activated Rac1 regulates the degradation of IκBα and the nuclear translocation of STAT3–NFκB complexes in starved cancer cells
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Kim SJ, Yoon S
- KMID: 2361518
- Exp Mol Med.
- 2016 May;48(5):e231.
- doi: 10.1038/emm.2016.17
In several human tumors, signal transducer and activator of transcription 3 (STAT3) and nuclear factor κB (NFκB) are activated and interact; how these STAT3–NFκB complexes are transported to the nucleus... -
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- Generation and characterization of integration-free induced pluripotent stem cells from patients with autoimmune disease
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Son MY, Lee MO, Jeon H, Seol B, Kim JH, Chang JS, Cho YS
- KMID: 2361519
- Exp Mol Med.
- 2016 May;48(5):e232.
- doi: 10.1038/emm.2016.27
Autoimmune diseases (AIDs), a heterogeneous group of immune-mediated disorders, are a major and growing health problem. Although AIDs are currently treated primarily with anti-inflammatory and immunosuppressive drugs, the use of... -
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- Proteomic analysis of novel targets associated with the enhancement of TrkA-induced SK-N-MC cancer cell death caused by NGF
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Jung EJ, Chung KH, Bae DW, Kim CW
- KMID: 2361522
- Exp Mol Med.
- 2016 May;48(5):e235.
- doi: 10.1038/emm.2016.33
Nerve growth factor (NGF) is known to regulate both cancer cell survival and death signaling, depending on the cellular circumstances, in various cell types. In this study, we showed that... -
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