- AMPK activators: mechanisms of action and physiological activities
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Kim J, Yang G, Kim Y, Kim J, Ha J
- KMID: 2361511
- Exp Mol Med.
- 2016 Apr;48(4):e224.
- doi: 10.1038/emm.2016.16
AMP-activated protein kinase (AMPK) is a central regulator of energy homeostasis, which coordinates metabolic pathways and thus balances nutrient supply with energy demand. Because of the favorable physiological outcomes of... -
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- Myosin heavy chain is stabilized by BCL-2 interacting cell death suppressor (BIS) in skeletal muscle
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Hong J, Park JS, Lee H, Jeong J, Yun HH, Kim HY, Ko YG, Lee JH
- KMID: 2361512
- Exp Mol Med.
- 2016 Apr;48(4):e225.
- doi: 10.1038/emm.2016.2
BCL-2 interacting cell death suppressor (BIS), which is ubiquitously expressed, has important roles in various cellular processes, such as apoptosis, the cellular stress response, migration and invasion and protein quality... -
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- Serum DKK-1 level in the development of ankylosing spondylitis and rheumatic arthritis: a meta-analysis
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Zhang L, Ouyang H, Xie Z, Liang ZH, Wu XW
- KMID: 2361515
- Exp Mol Med.
- 2016 Apr;48(4):e228.
- doi: 10.1038/emm.2016.12
To explore the association of serum Dickkopf-1 (DKK-1) levels with the development of ankylosing spondylitis (AS) and rheumatic arthritis (RA) in humans, databases including PubMed, EBSCO, Springerlink, Ovid, WANFANG and... -
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- Differentiation of human CD14+ monocytes: an experimental investigation of the optimal culture medium and evidence of a lack of differentiation along the endothelial line
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Safi W, Kuehnl A, Nüssler A, Eckstein H, Pelisek J
- KMID: 2361514
- Exp Mol Med.
- 2016 Apr;48(4):e227.
- doi: 10.1038/emm.2016.11
The aim of this study was to determine the optimal culturing media for human CD14+ monocytes and to evaluate whether these cells are capable of differentiating into vascular endothelial cells.... -
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- miR-148a is a downstream effector of X-box-binding protein 1 that silences Wnt10b during adipogenesis of 3T3-L1 cells
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Cho YM, Kim TM, Kim DH, Kim DH, Jeong SW, Kwon OJ
- KMID: 2361513
- Exp Mol Med.
- 2016 Apr;48(4):e226.
- doi: 10.1038/emm.2016.3
Wnt10b, an endogenous inhibitor of adipogenesis, maintains preadipocytes in an undifferentiated state by suppressing adipogenic transcription factors. We have previously demonstrated that Wnt10b transcription during adipogenesis is negatively regulated by... -
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- Small molecules that allosterically inhibit p21-activated kinase activity by binding to the regulatory p21-binding domain
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Kim DJ, Choi CK, Lee CS, Park MH, Tian X, Kim ND, Lee KI, Choi JK, Ahn JH, Shin EY, Shin I, Kim EG
- KMID: 2361516
- Exp Mol Med.
- 2016 Apr;48(4):e229.
- doi: 10.1038/emm.2016.13
p21-activated kinases (PAKs) are key regulators of actin dynamics, cell proliferation and cell survival. Deregulation of PAK activity contributes to the pathogenesis of various human diseases, including cancer and neurological... -
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