- Phospholipase D2 promotes degradation of hypoxia-inducible factor-1alpha independent of lipase activity
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Park MH, Bae SS, Choi KY, Min DS
- KMID: 2359883
- Exp Mol Med.
- 2015 Nov;47(11):e196.
- doi: 10.1038/emm.2015.87
Hypoxia-inducible factor-1alpha (HIF-1alpha) is a key transcriptional mediator that coordinates the expression of various genes involved in tumorigenesis in response to changes in oxygen tension. The stability of HIF-1alpha protein... -
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- Clinicopathological values of NBS1 and DNA damage response genes in epithelial ovarian cancers
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Lee YK, Park NH, Lee H
- KMID: 2359882
- Exp Mol Med.
- 2015 Nov;47(11):e195.
- doi: 10.1038/emm.2015.85
Epithelial ovarian cancers (EOCs) are highly lethal gynecological malignancies with a high recurrence rate. Therefore, developing prognostic markers for recurrence after chemotherapy is crucial for the treatment of ovarian cancers.... -
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- Clinical implications of proliferation activity in T1 or T2 male gastric cancer patients
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Kim YW, Eom BW, Kook MC, Kim HS, Kim MK, Hwang HL, Chandra V, Poojan S, Song Y, Koh JS, Bae CD, Ro J, Hong KM
- KMID: 2359880
- Exp Mol Med.
- 2015 Nov;47(11):e193.
- doi: 10.1038/emm.2015.79
Proliferation activity has already been established as a prognostic marker or as a marker for anticancer drug sensitivity. In gastric cancer, however, the prognostic significance of proliferation activity is still... -
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- Serum amyloid A inhibits RANKL-induced osteoclast formation
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Oh E, Lee HY, Kim HJ, Park YJ, Seo JK, Park JS, Bae YS
- KMID: 2359881
- Exp Mol Med.
- 2015 Nov;47(11):e194.
- doi: 10.1038/emm.2015.83
When mouse bone marrow-derived macrophages were stimulated with serum amyloid A (SAA), which is a major acute-phase protein, there was strong inhibition of osteoclast formation induced by the receptor activator... -
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