- Toward understanding the role of the neuron-specific BAF chromatin remodeling complex in memory formation
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Choi KY, Yoo M, Han JH
- KMID: 2070274
- Exp Mol Med.
- 2015 Apr;47(4):e155.
- doi: 10.1038/emm.2014.129
The long-term storage of memory requires the finely tuned coordination of intracellular signaling with the transcriptional, translational and epigenetic regulations of gene expression. Among the epigenetic mechanisms, however, we know... -
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- Polyubiquitin chain-dependent protein degradation in TRIM30 cytoplasmic bodies
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Choi UY, Choi WY, Hur JY, Kim YJ
- KMID: 2070278
- Exp Mol Med.
- 2015 Apr;47(4):e159.
- doi: 10.1038/emm.2015.12
Viral infection induces numerous tripartite motif (TRIM) proteins to control antiviral immune signaling and viral replication. Particularly, SPRY-containing TRIM proteins are found only in vertebrates and they control target protein... -
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- Gephyrin: a central GABAergic synapse organizer
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Choii G, Ko J
- KMID: 2070277
- Exp Mol Med.
- 2015 Apr;47(4):e158.
- doi: 10.1038/emm.2015.5
Gephyrin is a central element that anchors, clusters and stabilizes glycine and gamma-aminobutyric acid type A receptors at inhibitory synapses of the mammalian brain. It self-assembles into a hexagonal lattice... -
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- MyD88-BLT2-dependent cascade contributes to LPS-induced interleukin-6 production in mouse macrophage
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Lee AJ, Cho KJ, Kim JH
- KMID: 2070275
- Exp Mol Med.
- 2015 Apr;47(4):e156.
- doi: 10.1038/emm.2015.8
Endotoxic responses to bacterial lipopolysaccharide (LPS) are triggered by Toll-like receptor 4 (TLR4) and involve the production of inflammatory mediators, including interleukin-6 (IL-6), by macrophages. The detailed mechanism of IL-6... -
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- Polyphenols isolated from Broussonetia kazinoki prevent cytokine-induced beta-cell damage and the development of type 1 diabetes
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Bae UJ, Jang HY, Lim JM, Hua L, Ryu JH, Park BH
- KMID: 2070279
- Exp Mol Med.
- 2015 Apr;47(4):e160.
- doi: 10.1038/emm.2015.16
The axis of nuclear factor kappaB (NF-kappaB)-inducible NO synthase (iNOS)-nitric oxide plays a key role in cytokine- and streptozotocin-mediated pancreatic beta-cell damage. In this study, we investigated the effects of... -
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- Effects of MBL2 polymorphisms in patients with diisocyanate-induced occupational asthma
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Kim SH, Bae SJ, Palikhe S, Ye YM, Park HS
- KMID: 2070276
- Exp Mol Med.
- 2015 Apr;47(4):e157.
- doi: 10.1038/emm.2015.10
Diisocyanate (DI) is the most common cause of occupational asthma (OA) in Korea. Mannose-binding lectin (MBL) initiates the lectin complement activation pathway following oxidative stress and plays an important role... -
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