- An antibody reactive to the Gly63-Lys68 epitope of NT-proBNP exhibits O-glycosylation-independent binding
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Lee Y, Kim H, Chung J
- KMID: 2155379
- Exp Mol Med.
- 2014 Sep;46(9):e114.
- doi: 10.1038/emm.2014.57
The N-terminal fragment of prohormone brain natriuretic peptide (NT-proBNP) is a commonly used biomarker for the diagnosis of congestive heart failure, although its biological function is not well known. NT-proBNP... -
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- MiR-152 suppresses the proliferation and invasion of NSCLC cells by inhibiting FGF2
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Cheng Z, Ma R, Tan W, Zhang L
- KMID: 2155377
- Exp Mol Med.
- 2014 Sep;46(9):e112.
- doi: 10.1038/emm.2014.51
MicroRNAs (miRNAs) regulate the proliferation and metastasis of cancer cells. Here, we showed that miR-152 was downregulated in non-small-cell lung cancer (NSCLC) tissues and cell lines. Overexpression of miR-152 suppressed... -
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- Attenuation of airway inflammation by simvastatin and the implications for asthma treatment: is the jury still out?
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Liu JN, Suh DH, Yang EM, Lee SI, Park HS, Shin YS
- KMID: 2155378
- Exp Mol Med.
- 2014 Sep;46(9):e113.
- doi: 10.1038/emm.2014.55
Although some studies have explained the immunomodulatory effects of statins, the exact mechanisms and the therapeutic significance of these molecules remain to be elucidated. This study not only evaluated the... -
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- Preeclampsia serum-induced collagen I expression and intracellular calcium levels in arterial smooth muscle cells are mediated by the PLC-gamma1 pathway
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Jiang R, Teng Y, Huang Y, Gu J, Ma L, Li M, Zhou Y
- KMID: 2155380
- Exp Mol Med.
- 2014 Sep;46(9):e115.
- doi: 10.1038/emm.2014.59
In women with preeclampsia (PE), endothelial cell (EC) dysfunction can lead to altered secretion of paracrine factors that induce peripheral vasoconstriction and proteinuria. This study examined the hypothesis that PE... -
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