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Preeclampsia serum-induced collagen I expression and intracellular calcium levels in arterial smooth muscle cells are mediated by the PLC-gamma1 pathway

Jiang R, Teng Y, Huang Y, Gu J, Ma L, Li M, Zhou Y

In women with preeclampsia (PE), endothelial cell (EC) dysfunction can lead to altered secretion of paracrine factors that induce peripheral vasoconstriction and proteinuria. This study examined the hypothesis that PE...
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An antibody reactive to the Gly63-Lys68 epitope of NT-proBNP exhibits O-glycosylation-independent binding

Lee Y, Kim H, Chung J

The N-terminal fragment of prohormone brain natriuretic peptide (NT-proBNP) is a commonly used biomarker for the diagnosis of congestive heart failure, although its biological function is not well known. NT-proBNP...
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Attenuation of airway inflammation by simvastatin and the implications for asthma treatment: is the jury still out?

Liu JN, Suh DH, Yang EM, Lee SI, Park HS, Shin YS

Although some studies have explained the immunomodulatory effects of statins, the exact mechanisms and the therapeutic significance of these molecules remain to be elucidated. This study not only evaluated the...
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MiR-152 suppresses the proliferation and invasion of NSCLC cells by inhibiting FGF2

Cheng Z, Ma R, Tan W, Zhang L

MicroRNAs (miRNAs) regulate the proliferation and metastasis of cancer cells. Here, we showed that miR-152 was downregulated in non-small-cell lung cancer (NSCLC) tissues and cell lines. Overexpression of miR-152 suppressed...
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