- APE1/Ref-1 as an emerging therapeutic target for various human diseases: phytochemical modulation of its functions
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Thakur S, Sarkar B, Cholia RP, Gautam N, Dhiman M, Mantha AK
- KMID: 2155371
- Exp Mol Med.
- 2014 Jul;46(7):e106.
- doi: 10.1038/emm.2014.42
Apurinic/apyrimidinic endonuclease 1 (APE1) is a multifunctional enzyme involved in the base excision repair (BER) pathway, which repairs oxidative base damage caused by endogenous and exogenous agents. APE1 acts as... -
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- CDK5-dependent inhibitory phosphorylation of Drp1 during neuronal maturation
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Cho B, Cho HM, Kim HJ, Jeong J, Park SK, Hwang EM, Park JY, Kim WR, Kim H, Sun W
- KMID: 2155370
- Exp Mol Med.
- 2014 Jul;46(7):e105.
- doi: 10.1038/emm.2014.36
Mitochondrial functions are essential for the survival and function of neurons. Recently, it has been demonstrated that mitochondrial functions are highly associated with mitochondrial morphology, which is dynamically changed by... -
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- MiR-17-5p modulates osteoblastic differentiation and cell proliferation by targeting SMAD7 in non-traumatic osteonecrosis
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Jia J, Feng X, Xu W, Yang S, Zhang Q, Liu X, Feng Y, Dai Z
- KMID: 2155372
- Exp Mol Med.
- 2014 Jul;46(7):e107.
- doi: 10.1038/emm.2014.43
MicroRNAs (miRNAs) have recently been recognized to have a role in human orthopedic disorders. The objective of our study was to explore the expression profile and biological function of miRNA-17-5p... -
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- Kruppel-like factor 4 mediates lysophosphatidic acid-stimulated migration and proliferation of PC3M prostate cancer cells
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Shin SH, Kwon YW, Heo SC, Jeong GO, Kim BR, Seo EJ, Kim JH
- KMID: 2155369
- Exp Mol Med.
- 2014 Jul;46(7):e104.
- doi: 10.1038/emm.2014.34
Prostate cancer is the most frequently diagnosed malignancy and the second leading cause of cancer mortality among men in the United States. Accumulating evidence suggests that lysophosphatidic acid (LPA) serves... -
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