- Inhibition of phospholipase D2 induces autophagy in colorectal cancer cells
-
Hwang WC, Kim MK, Song JH, Choi KY, Min DS
- KMID: 2155389
- Exp Mol Med.
- 2014 Dec;46(12):e124.
- doi: 10.1038/emm.2014.74
Autophagy is a conserved lysosomal self-digestion process used for the breakdown of long-lived proteins and damaged organelles, and it is associated with a number of pathological processes, including cancer. Phospholipase... -
- CITED
-
- Close
- SHARE
-
- Close
- Phospholipase D activates HIF-1-VEGF pathway via phosphatidic acid
-
Han S, Huh J, Kim W, Jeong S, Min DS, Jung Y
- KMID: 2155391
- Exp Mol Med.
- 2014 Dec;46(12):e126.
- doi: 10.1038/emm.2014.86
Growth factor-stimulated phospholipase D (PLD) catalyzes the hydrolysis of phosphatidylcholine (PC), generating phosphatidic acid (PA) which may act as a second messenger during cell proliferation and survival. Therefore, PLD is... -
- CITED
-
- Close
- SHARE
-
- Close
- Omega-3 polyunsaturated fatty acid and ursodeoxycholic acid have an additive effect in attenuating diet-induced nonalcoholic steatohepatitis in mice
-
Kim JK, Lee KS, Lee DK, Lee SY, Chang HY, Choi J, Lee JI
- KMID: 2155392
- Exp Mol Med.
- 2014 Dec;46(12):e127.
- doi: 10.1038/emm.2014.90
Nonalcoholic steatohepatitis (NASH) can progress into liver cirrhosis; however, no definite treatment is available. Omega-3 polyunsaturated fatty acid (omega-3) has been reported to alleviate experimental NASH, although its beneficial effect... -
- CITED
-
- Close
- SHARE
-
- Close
- Role of LPA and the Hippo pathway on apoptosis in salivary gland epithelial cells
-
Hwang SM, Jin M, Shin YH, Ki Choi S, Namkoong E, Kim M, Park MY, Park K
- KMID: 2155390
- Exp Mol Med.
- 2014 Dec;46(12):e125.
- doi: 10.1038/emm.2014.77
Lysophosphatidic acid (LPA) is a bioactive lysophospholipid involved in numerous physiological responses. However, the expression of LPA receptors and the role of the Hippo signaling pathway in epithelial cells have... -
- CITED
-
- Close
- SHARE
-
- Close
