- Phenylpropanoids in radioregulation: double edged sword
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Kim W, Seong KM, Youn B
- KMID: 1107373
- Exp Mol Med.
- 2011 Jun;43(6):323-333.
- doi: 10.3858/emm.2011.43.6.034
Radiotherapy, frequently used for treatment of solid tumors, carries two main obstacles including acquired radioresistance in cancer cells during radiotherapy and normal tissue injury. Phenylpropanoids, which are naturally occurring phytochemicals... -
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- Effects of combined mechanical stimulation on the proliferation and differentiation of pre-osteoblasts
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Kang KS, Lee SJ, Lee H, Moon W, Cho DW
- KMID: 1107378
- Exp Mol Med.
- 2011 Jun;43(6):367-373.
- doi: 10.3858/emm.2011.43.6.040
We observed how combined mechanical stimuli affect the proliferation and differentiation of pre-osteoblasts. For this research, a bioreactor system was developed that can simultaneously stimulate cells with cyclic strain and... -
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- Snapshot of degenerative aging of porcine intervertebral disc: a model to unravel the molecular mechanisms
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Cho H, Park SH, Lee S, Kang M, Hasty KA, Kim SJ
- KMID: 1107374
- Exp Mol Med.
- 2011 Jun;43(6):334-340.
- doi: 10.3858/emm.2011.43.6.036
Larger animal models, such as porcine, have been validated as appropriate models of the human disc with respect to biomechanics and biochemistry. They are advantageous for research as the models... -
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- Antifibrotic effects of magnesium lithospermate B on hepatic stellate cells and thioacetamide-induced cirrhotic rats
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Paik YH, Yoon YJ, Lee HC, Jung MK, Kang SH, Chung SI, Kim JK, Cho JY, Lee KS, Han KH
- KMID: 1107375
- Exp Mol Med.
- 2011 Jun;43(6):341-349.
- doi: 10.3858/emm.2011.43.6.037
Magnesium lithospermate B (MLB) is one of the major active components of Salvia miltiorrhizae. The anti-oxidative effects of Salvia miltiorrhizae have been previously reported. The aim of this study was... -
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- Identification of miR-23a as a novel microRNA normalizer for relative quantification in human uterine cervical tissues
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Shen Y, Li Y, Ye F, Wang F, Wan X, Lu W, Xie X
- KMID: 1107377
- Exp Mol Med.
- 2011 Jun;43(6):358-366.
- doi: 10.3858/emm.2011.43.6.039
Quantitative real-time RT-PCR (RT-qPCR) is being widely used in microRNA expression research. However, few reports detailed a robust identification and validation strategy for suitable reference genes for normalisation in microRNA... -
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- Regulation of B cell activating factor (BAFF) receptor expression by NF-kappaB signaling in rheumatoid arthritis B cells
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Woo YJ, Yoon BY, Jhun JY, Oh HJ, Min S, Cho ML, Park SH, Kim HY, Min JK
- KMID: 1107376
- Exp Mol Med.
- 2011 Jun;43(6):350-357.
- doi: 10.3858/emm.2011.43.6.038
B cells play an important role in the pathogenesis of rheumatoid arthritis (RA). High levels of B cell activating factor (BAFF) are detected in autoimmune diseases. BAFF and BAFF receptor... -
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- Polymorphisms in genes involved in innate immunity and susceptibility to benzene-induced hematotoxicity
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Shen M, Zhang L, Lee KM, Vermeulen , Hosgood HD, Li G, Yin S, Rothman N, Chanock S, Smith MT, Lan Q
- KMID: 1107379
- Exp Mol Med.
- 2011 Jun;43(6):374-378.
- doi: 10.3858/emm.2011.43.6.041
Benzene, a recognized hematotoxicant and carcinogen, can damage the human immune system. We studied the association between single nucleotide polymorphisms (SNPs) in genes involved in innate immunity and benzene hematotoxicity... -
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