- Erratum
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Lee W, Choi HI, Kim MJ, Park SY
- KMID: 991624
- Exp Mol Med.
- 2011 Jan;43(1):62-62.
- doi: 10.3858/emm.2011.43.1.015
No abstract available. -
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- Genetic controls of Th17 cell differentiation and plasticity
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Dong C
- KMID: 991617
- Exp Mol Med.
- 2011 Jan;43(1):1-6.
- doi: 10.3858/emm.2011.43.1.007
CD4+ T lymphocytes play a major role in regulation of adaptive immunity. Upon activation, naive T cells differentiate into different functional subsets. In addition to the classical Th1 and Th2... -
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- Biliverdin reductase A in the prevention of cellular senescence against oxidative stress
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Kim SY, Kang HT, Choi HR, Park SC
- KMID: 991619
- Exp Mol Med.
- 2011 Jan;43(1):15-23.
- doi: 10.3858/emm.2011.43.1.002
Biliverdin reductase A (BLVRA), an enzyme that converts biliverdin to bilirubin, has recently emerged as a key regulator of the cellular redox cycle. However, the role of BLVRA in the... -
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- Paxilline enhances TRAIL-mediated apoptosis of glioma cells via modulation of c-FLIP, survivin and DR5
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Kang YJ, Kim IY, Kim EH, Yoon MJ, Kim SU, Kwon TK, Choi KS
- KMID: 991620
- Exp Mol Med.
- 2011 Jan;43(1):24-34.
- doi: 10.3858/emm.2011.43.1.003
Tumor necrosis factor-related apoptosis-induced ligand (TRAIL) induces apoptosis selectively in cancer cells while sparing normal cells. However, many cancer cells are resistant to TRAIL-induced cell death. Here, we report that... -
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- Clusterin protects H9c2 cardiomyocytes from oxidative stress-induced apoptosis via Akt/GSK-3beta signaling pathway
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Jun HO, Kim DH, Lee SW, Lee HS, Seo JH, Kim JH, Kim JH, Yu YS, Min BH, Kim KW
- KMID: 991623
- Exp Mol Med.
- 2011 Jan;43(1):53-61.
- doi: 10.3858/emm.2011.43.1.006
Clusterin is a secretory glycoprotein, which is highly up-regulated in a variety of normal and injury tissues undergoing apoptosis including infarct region of the myocardium. Here, we report that clusterin... -
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- Associations between DRDs and schizophrenia in a Korean population: multi-stage association analyses
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Lee KY, Joo EJ, Ji YI, Kim DH, Park J, Chung IW, Lee SI, Joo YH, Ahn YM, Song JY, Kim YS
- KMID: 991622
- Exp Mol Med.
- 2011 Jan;43(1):44-52.
- doi: 10.3858/emm.2011.43.1.005
The dysregulation of the dopaminergic system has been implicated in the pathophysiology of major psychosis, including schizophrenia, with dopamine receptor genes (DRDs) presently targeted as the most promising candidate genes.... -
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- Microglial P2X7 receptor expression is accompanied by neuronal damage in the cerebral cortex of the APPswe/PS1dE9 mouse model of Alzheimer's disease
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Lee HG, Won SM, Gwag BJ, Lee YB
- KMID: 991618
- Exp Mol Med.
- 2011 Jan;43(1):7-14.
- doi: 10.3858/emm.2011.43.1.001
The possibility that P2X7 receptor (P2X7R) expression in microglia would mediate neuronal damage via reactive oxygen species (ROS) production was examined in the APPswe/PS1dE9 mouse model of Alzheimer's disease (AD).... -
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- Mast cells play a key role in Th2 cytokine-dependent asthma model through production of adhesion molecules by liberation of TNF-alpha
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Chai OH, Han EH, Lee HK, Song CH
- KMID: 991621
- Exp Mol Med.
- 2011 Jan;43(1):35-43.
- doi: 10.3858/emm.2011.43.1.004
Mast cells are well recognized as key cells in allergic reactions, such as asthma and allergic airway diseases. However, the effects of mast cells and TNF-alpha on T-helper type 2... -
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