Skip Navigation
Skip to contents
Filter

ARTICLE TYPE

PUBLICATION DATE

7 results
Display

Triptolide downregulates human GD3 synthase (hST8Sia I) gene expression in SK-MEL-2 human melanoma cells

Kwon HY, Kim SJ, Kim CH, Son SW, Kim KS, Lee JH, Do SI, Lee YC

In this study, we have shown that gene expression of human GD3 synthase (hST8Sia I) is suppressed by triptolide (TPL) in human melanoma SK-MEL-2 cells. To elucidate the mechanism underlying...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Novel deletion of the E3A ubiquitin protein ligase gene detected by multiplex ligation-dependent probe amplification in a patient with Angelman syndrome

Cali F, Ragalmuto , Chiavetta , Calabrese , Fichera M, Vinci M, Ruggeri G, Schinocca , Sturnio M, Romano S, Romano V, Elia M

Angelman syndrome (AS) is a severe neurobehavioural disorder caused by failure of expression of the maternal copy of the imprinted domain located on 15q11-q13. There are different mechanisms leading to...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Low-dose UVB irradiation stimulates matrix metalloproteinase-1 expression via a BLT2-linked pathway in HaCaT cells

Kim C, Ryu HC, Kim JH

Skin exposure to low-dose ultraviolet B (UVB) light up-regulates the expression of matrix metalloproteinase-1 (MMP-1), thus contributing to premature skin aging (photo-aging). Although cyclooxygenase-2 (COX-2) and its product, prostaglandin E2...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Systemic LPS administration induces brain inflammation but not dopaminergic neuronal death in the substantia nigra

Jeong HK, Jou I, Joe EH

It has been suggested that brain inflammation is important in aggravation of brain damage and/or that inflammation causes neurodegenerative diseases including Parkinson's disease (PD). Recently, systemic inflammation has also emerged...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Baicalein protects HT22 murine hippocampal neuronal cells against endoplasmic reticulum stress-induced apoptosis through inhibition of reactive oxygen species production and CHOP induction

Choi JH, Choi AY, Yoon H, Choe W, Yoon KS, Ha J, Yeo EJ, Kang I

Baicalein is one of the major flavonoids in Scutellaria baicalensis Georgi and possesses various effects, including cytoprotection and anti-inflammation. Because endoplasmic reticulum (ER) stress has been implicated in neurodegenerative diseases,...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Nuclear factor of activated T cells negatively regulates expression of the tumor necrosis factor receptor-related 2 gene in T cells

Kim WK, Sul OJ, Kwak JS, Hur HY, Latour AM, Koller BH, Kwon BS, Jeong CS

Tumor necrosis factor receptor-related 2 (TR2, HVEM or TNFRSF-14) plays an important role in immune responses, however, the mechanisms regulating its expression are unclear. To understand the control of TR2...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Genome-wide linkage analysis for ocular and nasal anthropometric traits in a Mongolian population

Im SW, Kim HJ, Lee MK, Yi JH, Jargal G, Sung J, Cho SI, Kim JI

Anthropometric traits for eyes and nose are complex quantitative traits influenced by genetic and environmental factors. To date, there have been few reports on the contribution of genetic influence to...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2020 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr