- Alterations of epinephrine-induced gluconeogenesis in aging
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Kim K, Cho SC, Cova A, Jang IS, Park SC
- KMID: 1123807
- Exp Mol Med.
- 2009 May;41(5):334-340.
- doi: 10.3858/emm.2009.41.5.037
The effects of glucagon and epinephrine on gluconeogenesis in young (4 month) and old (24 month) Fisher 344 rat hepatocytes were compared. In contrast to glucagon, which had a similar... -
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- Chromosomal instability is more frequent in metastasized than in non-metastasized pulmonary carcinoids but is not a reliable predictor of metastatic potential
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Warth A, Herpel E, Krysa S, Hoffmann H, Schnabel P, Schirmacher P, Mechtersheimer G, Blaker H
- KMID: 1123809
- Exp Mol Med.
- 2009 May;41(5):349-353.
- doi: 10.3858/emm.2009.41.5.039
Pulmonary carcinoids are infrequent neoplasms of the lung that normally display a less aggressive biological behavior compared to small cell and non-small cell lung cancers. Approximately 15-25% of carcinoids, in... -
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- Tunicamycin enhances TRAIL-induced apoptosis by inhibition of cyclin D1 and the subsequent downregulation of survivin
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Zhang HY, Du ZX, Liu BQ, Gao YY, Meng X, Guan Y, Deng WW, Wang HQ
- KMID: 1123811
- Exp Mol Med.
- 2009 May;41(5):362-369.
- doi: 10.3858/emm.2009.41.5.041
TNF-related apoptosis-inducing ligand (TRAIL) has been proposed as a promising cancer therapy that preferentially induces apoptosis in cancer cells, but not most normal tissues. However, many cancers are resistant to... -
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- ICAM-1/LFA-1 interaction contributes to the induction of endothelial cell-cell separation: implication for enhanced leukocyte diapedesis
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Wee H, Oh HM, Jo JH, Jun CD
- KMID: 1123808
- Exp Mol Med.
- 2009 May;41(5):341-348.
- doi: 10.3858/emm.2009.41.5.038
The basic route and mechanism for diapedesis has not yet to be fully defined. Here we present evidence that "cell-cell separation" between endothelial cells (ECs) may provide a route for... -
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- LL-37 inhibits serum amyloid A-induced IL-8 production in human neutrophils
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Lee HY, Kim SD, Shim JW, Lee SY, Yun J, Bae YS
- KMID: 1123806
- Exp Mol Med.
- 2009 May;41(5):325-333.
- doi: 10.3858/emm.2009.41.5.036
Serum amyloid A (SAA) has been regarded as an important mediator of inflammatory responses. The effect of several formyl peptide receptor-like 1 (FPRL1) ligands on the production of IL-8 by... -
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- Calcitonin induces connective tissue growth factor through ERK1/2 signaling in renal tubular cells
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Nakamura M, Ozaki T, Ishii A, Konishi M, Tsubota Y, Furui T, Tsuda H, Mori I, Ota K, Kakudo K
- KMID: 1123804
- Exp Mol Med.
- 2009 May;41(5):307-314.
- doi: 10.3858/emm.2009.41.5.034
Calcitonin (CT), a polypeptide hormone, plays important roles in a variety of physiological processes. CT has been used clinically to treat osteoporosis and humoral hypercalcemia of malignancy. In order to... -
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- Soluble mediators from mesenchymal stem cells suppress T cell proliferation by inducing IL-10
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Yang SH, Park MJ, Yoon IH, Kim SY, Hong SH, Shin JY, Nam HY, Kim YH, Kim B, Park CG
- KMID: 1123805
- Exp Mol Med.
- 2009 May;41(5):315-324.
- doi: 10.3858/emm.2009.41.5.035
Mesenchymal stem cells (MSCs) can inhibit T cell proliferation; however, the underlying mechanisms are not clear. In this study, we investigated the mechanisms of the immunoregulatory activity of MSCs on... -
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- Polymorphisms of COTL1 gene identified by proteomic approach and their association with autoimmune disorders
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Jin EH, Shim SC, Kim HG, Chae SC, Chung HT
- KMID: 1123810
- Exp Mol Med.
- 2009 May;41(5):354-361.
- doi: 10.3858/emm.2009.41.5.040
To select candidate genes, we attempted to comparative analysis of protein levels between rheumatoid arthritis (RA) patients and healthy controls by two-dimensional electrophoresis (2-DE) and matrix-assisted laser desorption ionization mass... -
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- Repression of TNF-alpha-induced IL-8 expression by the glucocorticoid receptor-beta involves inhibition of histone H4 acetylation
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Kim SH, Kim DH, Lavender P, Seo JH, Kim YS, Park JS, Kwak SJ, Jee YK
- KMID: 1123803
- Exp Mol Med.
- 2009 May;41(5):297-306.
- doi: 10.3858/emm.2009.41.5.033
Increased expression of a number of proinflammatory genes, including IL-8, is associated with inflammatory conditions such as asthma. Glucocorticoid receptor (GR)beta, one of the GR isoforms, has been suggested to... -
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