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Erratum: Efficient gene delivery in differentiated human embryonic stem cells. Exp Mol Med 2005;37:36-44

Kim JH, Do HJ, Choi SJ, Cho HJ, Park KH, Yang HM, Lee SH, Kim DK, Kwack KB, Oh SK, Moon SY, Cha KY, Chung HM

  • KMID: 1098094
  • Exp Mol Med.
  • 2006 Oct;38(5):589-589.
The authors would like to amend a reference (Lee et al., 2003) that was cited in "Cell culture" section of "Materials and Methods". Instead of "(Lee et al., 2003)", we...
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Putative association of RUNX1 polymorphisms with IgE levels in a Korean population

Chae SC, Park BL, Park CS, Ryu HJ, Yang YS, Lee SO, Choi YH, Kim EM, Uh ST, Kim YH, Kim KK, Oh B, Chung HT, Kimm K, Shin HD

  • KMID: 1098093
  • Exp Mol Med.
  • 2006 Oct;38(5):583-588.
RUNX1, a member of the runt domain gene family of transcription factors, encodes a heterodimeric transcription factor and regulates the expression of various genes related to hematopoiesis and myeloid differentiation....
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Immunosuppression of xenograft rejection in porcine kidney PK15 cells by porcine IL-18

Choi YS, Kim YK, Shim JH, Kim EM, Kang HS, Yoon DY, Muneta Y, Myung PK

  • KMID: 1098092
  • Exp Mol Med.
  • 2006 Oct;38(5):574-582.
Xenotransplantation, the transplantation of cells, tissues or organs between individuals of different species, would resolve the current shortage of organs, but rejection remains the major hurdle to successful xenotransplantation. In...
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An alternatively spliced form of Met receptor is tumorigenic

Lee JH, Gao CF, Lee CC, Kim MD, Vande Woude GF

  • KMID: 1098091
  • Exp Mol Med.
  • 2006 Oct;38(5):565-573.
The Met tyrosine kinase receptor is a widely expressed molecule, which mediates pleiotropic cellular responses following activation by its ligand, hepatocyte growth factor/scatter factor (HGF/SF). Previously, one of the authors...
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Low-dose radiation response of the p21(WAF1/CIP1) gene promoter transduced by adeno-associated virus vector

Nenoi M, Daino K, Ichimura S, Takahash S, Akuta T

  • KMID: 1098090
  • Exp Mol Med.
  • 2006 Oct;38(5):553-564.
In cancer gene therapy, restriction of antitumor transgene expression in a radiation field by use of ionizing radiation-inducible promoters is one of the promising approaches for tumor-specific gene delivery. Although...
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Cysteine-179 of I kappa B kinase beta plays a critical role in enzyme activation by promoting phosphorylation of activation loop serines

Byun MS, Choi J, Jue DM

  • KMID: 1098089
  • Exp Mol Med.
  • 2006 Oct;38(5):546-552.
I kappa B kinase beta (IKK beta) subunit of IKK complex is essential for the activation of NF-kappa B in response to various proinflammatory signals. Cys-179 in the activation loop...
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Doxorubicin-induced reactive oxygen species generation and intracellular Ca2+increase are reciprocally modulated in rat cardiomyocytes

Kim SY, Kim SJ, Kim BJ, Rah SY, Chung SM, Im MJ, Kim UH

  • KMID: 1098088
  • Exp Mol Med.
  • 2006 Oct;38(5):535-545.
Doxorubicin (DOX) is one of the most potent anticancer drugs and induces acute cardiac arrhythmias and chronic cumulative cardiomyopathy. Though DOX-induced cardiotoxicity is known to be caused mainly by ROS...
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Catechins inhibit angiotensin II-induced vascular smooth muscle cell proliferation via mitogen-activated protein kinase pathway

Won SM, Park YH, Kim HJ, Park KM, Lee WJ

  • KMID: 1098087
  • Exp Mol Med.
  • 2006 Oct;38(5):525-534.
Catechins, components of green tea, reduce the incidence of cardiovascular diseases such as atherosclerosis. Angiotensin II (Ang II) is highly implicated in the proliferation of vascular smooth muscle cells (VSMC),...
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Methionine synthase reductase polymorphisms are associated with serum osteocalcin levels in postmenopausal women

Kim DJ, Park BL, Koh JM, Kim GS, Kim LH, Cheong HS, Shin HD, Hong JM, Kim TH, Shin HI, Park EK, Kim SY

  • KMID: 1098086
  • Exp Mol Med.
  • 2006 Oct;38(5):519-524.
Homocysteine (Hcy) is thought to play an important role in the development of osteoporosis and fracture. Methionine synthase reductase (MTRR) is an enzyme involved in the conversion of Hcy to...
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Inhibitory effect of Hsp70 on angiotensin II-induced vascular smooth muscle cell hypertrophy

Zheng Y, Im CN, Seo JS

  • KMID: 1098085
  • Exp Mol Med.
  • 2006 Oct;38(5):509-518.
Angiotensin II (Ang II), which is an important mediator of both vascular responsiveness and growth, has been shown to induce vascular smooth muscle cell (VSMC) hypertrophy via the activation of...
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KR-31831, a new synthetic anti-ischemic agent, inhibits in vivo and in vitro angiogenesis

Yi EY, Park SY, Song HS, Son MJ, Yi KY, Yoo SE, Kim YJ

  • KMID: 1098084
  • Exp Mol Med.
  • 2006 Oct;38(5):502-508.
Angiogenesis is considered to be an integral process to the growth and spread of solid tumors. Anti-angiogenesis therapy recently has been found to be one of the most promising anti-cancer...
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Maintenance of CD8+T-cell anergy by CD4+CD25+ regulatory T cells in chronic graft-versus-host disease

Kim J, Kim HJ, Choi WS, Nam SH, Cho HR, Kwon B

  • KMID: 1098083
  • Exp Mol Med.
  • 2006 Oct;38(5):494-501.
In a murine model of systemic lupus erythematosus (SLE)-like chronic graft-versus-host disease (cGVHD), donor CD8+T cells rapidly fall into anergy to host cells, while donor CD4+T cells hyperactivate B cells...
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Identification of a novel murine organic anion transporter like protein 1 (OATLP1) expressed in the kidney

Jung SM, Lee WK, Kwak JO, Jung SY, Park J, Kim WY, Kim J, Cha SH

  • KMID: 1098082
  • Exp Mol Med.
  • 2006 Oct;38(5):485-493.
The organic anion transporters (OATs) are expressed in various tissues, primarily in the kidney and liver, but they are also expressed in the placenta, small intestine, and the choroid plexus,...
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Increase of NKG2D ligands and sensitivity to NK cell-mediated cytotoxicity of tumor cells by heat shock and ionizing radiation

Kim JY, Son YO, Park SW, Bae JH, Chung JS, Kim HH, Chung BS, Kim SH, Kang CD

  • KMID: 1098081
  • Exp Mol Med.
  • 2006 Oct;38(5):474-484.
In this study, we have investigated if current cancer therapeutic modalities including hyperthermia and ionizing radiation can increase the expression of NKG2D ligands in human cancer cell lines. The expressions...
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Expression of glucocorticoid receptor mRNAs in glucocorticoid-resistant nasal polyps

Choi BR, Kwon JH, Gong SJ, Kwon MS, Cho JH, Kim JH, Oh S, Roh HJ, Kim DE

  • KMID: 1098080
  • Exp Mol Med.
  • 2006 Oct;38(5):466-473.
Glucocorticoids (GCs) are the most effective group of medications available to treat inflammation. Although most patients with inflammation respond to GC, a small group of patients exhibit persistent GC-resistance with...
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Overexpression of nicotinamide N-methyltransferase in gastric cancer tissues and its potential post-translational modification

Lim BH, Cho BI, Kim YN, Kim JW, Park ST, Lee CW

  • KMID: 1098079
  • Exp Mol Med.
  • 2006 Oct;38(5):455-465.
Gastric cancer is one of the most common cancers worldwide. The purpose of this study was to find out potential markers for gastric cancer. Tumor and normal tissues from 152...
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