- Coordinated transcriptional regulation of calmegin, a testis-specific molecular chaperon, by histone deacetylase and CpG methyltransferase
-
Kim DH, Shim JS, Kwon HJ
- KMID: 1089460
- Exp Mol Med.
- 2005 Oct;37(5):492-496.
Calmegin is a testis-specific molecular chaperon playing a key role in spermatogenesis. However, the transcriptional regulatory mechanisms for calmegin expression are entirely unknown. Herein, we revealed that calmegin is transcriptionally... -
- CITED
-
- Close
- SHARE
-
- Close
- Alternative therapy of earth elements increases the chondroprotective effects of chondroitin sulfate in mice
-
Caraglia M, Beninati S, Giuberti G, D'Alessandro A, Lentini A, Abbruzzese A, Bove G, Landolfi F, Rossi F, Lampa E, Costantino M
- KMID: 1089457
- Exp Mol Med.
- 2005 Oct;37(5):476-481.
The administration of mineral sulphur water is an alternative experimental approach for the treatment of rheumatic diseases, such as osteoarthritis (OA), that cause the degeneration of bone and cartilage and... -
- CITED
-
- Close
- SHARE
-
- Close
- Detection of single nucleotide insertion of BCR/ABL region in imatinib-resistant human myelogenous leukemia SR-1 cells
-
Park TH, Kwon HC, Kim HJ, Han JY, Jeong JS, Han H, Seo CY, Kwak JY, Park JI
- KMID: 1089462
- Exp Mol Med.
- 2005 Oct;37(5):507-511.
Imatinib mesylate is a selective Bcr/Abl kinase inhibitor and an effective anticancer agent for Bcr/Abl-positive chronic myelogenous leukemia. Most patients in chronic phase maintain durable responses; however, many in blast... -
- CITED
-
- Close
- SHARE
-
- Close
- Heat shock protein 27 interacts with vimentin and prevents insolubilization of vimentin subunits induced by cadmium
-
Lee JS, Zhang MH, Yun EK, Geum D, Kim K, Kim TH, Lim YS, Seo JS
- KMID: 1089452
- Exp Mol Med.
- 2005 Oct;37(5):427-435.
Vimentin is an intermediate filament that regulates cell attachment and subcellular organization. In this study, vimentin filaments were morphologically altered, and its soluble subunits were rapidly reduced via cadmium chloride... -
- CITED
-
- Close
- SHARE
-
- Close
- Centrosome amplification and multinuclear phenotypes are Induced by hydrogen peroxide
-
Chae S, Yun C, Um H, Lee JH, Cho H
- KMID: 1089458
- Exp Mol Med.
- 2005 Oct;37(5):482-487.
Multinucleated cells resulted from mitosis defect have been noted in pathophysiological states of the cells such as inflammation, senescence and cancer. Since oxidative stress has been known to correlate with... -
- CITED
-
- Close
- SHARE
-
- Close
- Characterization of newly established oral cancer cell lines derived from six squamous cell carcinoma and two mucoepidermoid carcinoma cells
-
Lee EJ, Kim J, Lee SA, Kim EJ, Chun YC, Ryu MH, Yook JI
- KMID: 1089447
- Exp Mol Med.
- 2005 Oct;37(5):379-390.
Since genetic abnormalities of human cancer are greatly geographically dependent, cultural and environmental backgrounds are thought to be closely related to the carcinogenic process. In the present study, eight human... -
- CITED
-
- Close
- SHARE
-
- Close
- Menin represses JunD transcriptional activity in protein kinase Ctheta-mediated Nur77 expression
-
Kim H, Lee JE, Kim BY, Cho EJ, Kim ST, Youn HD
- KMID: 1089456
- Exp Mol Med.
- 2005 Oct;37(5):466-475.
TCR signaling leading to thymocyte apoptosis is mediated through the expression of the Nur77 family of orphan nuclear receptors. It has been shown that the Nur77 promoter is activated by... -
- CITED
-
- Close
- SHARE
-
- Close
- Transcription repression of a CCAAT-binding transcription factor CBF/HSP70 by p53
-
Chae HD, Yun J, Shi D
- KMID: 1089459
- Exp Mol Med.
- 2005 Oct;37(5):488-491.
NF-Y transcription factor binds to CCAAT boxes on promoters of cell cycle regulatory genes such as cdc2, cyclin B, cdc25C, and cyclin A. We previously reported that the DNA binding... -
- CITED
-
- Close
- SHARE
-
- Close
- Natural compounds, fraxin and chemicals structurally related to fraxin protect cells from oxidative stress
-
Whang WK, Park HS, Ham I, Oh M, Namkoong H, Kim HK, Hwang DW, Hur SY, Kim TE, Park YG, Kim JR, Kim JW
- KMID: 1089453
- Exp Mol Med.
- 2005 Oct;37(5):436-446.
Coumarins comprise a group of natural phenolic compounds found in a variety of plant sources. In view of the established low toxicity, relative cheapness, presence in the diet and occurrence... -
- CITED
-
- Close
- SHARE
-
- Close
- Involvement of protein kinase C pathway in UVC-stimulated phospholipase D2 activity in Vero 76 cells
-
Kim S, Choi MS, Choi MU
- KMID: 1089451
- Exp Mol Med.
- 2005 Oct;37(5):418-426.
Phospholipase D (PLD) activity is known to be related to oxidant-induced cellular signaling and membrane disturbance. Previously, an induction of PLD activity in various cell lines by X-ray irradiation was... -
- CITED
-
- Close
- SHARE
-
- Close
- Up-regulation of defense enzymes is responsible for low reactive oxygen species in malignant prostate cancer cells
-
Lim HW, Hong S, Jin W, Lim S, Kim SJ, Kang HJ, Park EH, Ahn K, Lim CJ
- KMID: 1089461
- Exp Mol Med.
- 2005 Oct;37(5):497-506.
Reactive oxygen species (ROS) are involved in a diversity of important phenomena in the process of tumor development. To investigate the alterations of oxidative stress and their related systems in... -
- CITED
-
- Close
- SHARE
-
- Close
- PTEN/MMAC1 enhances the growth inhibition by anticancer drugs with downregulation of IGF-II expression in gastric cancer cells
-
Hwang PH, Kim SY, Lee JC, Kim SJ, Yi HK, Lee DY
- KMID: 1089448
- Exp Mol Med.
- 2005 Oct;37(5):391-398.
PTEN/MMAC1 is a tumor suppressor gene that is mutated in a variety of advanced and metastatic cancers. Its major function is likely to be the phosphatase activity that regulates the... -
- CITED
-
- Close
- SHARE
-
- Close
- Efficient culture system for human embryonic stem cells using autologous human embryonic stem cell-derived feeder cells
-
Yoo SJ, Yoon BS, Kim JM, Song JM, Roh SI, You S, Yoon HS
- KMID: 1089449
- Exp Mol Med.
- 2005 Oct;37(5):399-407.
Human embryonic stem cells (hESCs) need feeder cells for their maintenance in an undifferentiated state. In conventional culture systems, mouse embryonic fibroblasts (MEFs) serve as feeder cells to maintain hESCs.... -
- CITED
-
- Close
- SHARE
-
- Close
- The extracellular calcium sensing receptor is expressed in mouse mesangial cells and modulates cell proliferation
-
Kwak JO, Kwak J, Kim HW, Oh KJ, Kim YT, Jung SM, Cha SH
- KMID: 1089455
- Exp Mol Med.
- 2005 Oct;37(5):457-465.
The extracellular calcium sensing receptor (CaSR) belongs to the type III family of G-protein-coupled receptors, a family that comprises the metabotropic glutamate receptor and the putative vomeronasal organ receptors. The... -
- CITED
-
- Close
- SHARE
-
- Close
- Roles of TNF-alpha and IgE in the late phase of contact hypersensitivity induced by trimellitic anhydride
-
Chai OH, Lee HK, Lee YC, Lee MS, Han EH, Kim HT, Song CH
- KMID: 1089450
- Exp Mol Med.
- 2005 Oct;37(5):408-417.
Trimellitic anhydride (TMA) is widely used industrially to make epoxy and alkyd resins, plasticizers and surfactants. The purpose of this study was to investigate whether contact hypersensitivity (CHS) is induced... -
- CITED
-
- Close
- SHARE
-
- Close
- Cardiac expression profiles of the naked DNA vectors encoding vascular endothelial growth factor and basic fibroblast growth factor
-
Lee JS, Byun J, Kim JM, Kim CY, Kim BM, Chung JH, Jang Y, Kim DK
- KMID: 1089454
- Exp Mol Med.
- 2005 Oct;37(5):447-456.
We investigated expression profiles and biological effects of the naked DNA vectors in the heart. To this end, naked DNA vector was injected into the apex of the beating rat... -
- CITED
-
- Close
- SHARE
-
- Close
