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Serotonin transporter mRNA expression in the dorsal raphe nucleus of a tumor bearing mouse

Jahng JW, Choi SH, Cha MJ, Kim NY, Hwang SJ, Lee JH

  • KMID: 1033103
  • Exp Mol Med.
  • 2005 Feb;37(1):65-69.
This study was conducted to determine if an oral squamous cell carcinoma alters mRNA expression of serotonin transporter (5-HTT) in the central nervous system. KB cell line derived from a...
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Neurotoxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin in cerebellar granule cells

Kim SY, Yang JH

  • KMID: 1033102
  • Exp Mol Med.
  • 2005 Feb;37(1):58-64.
An environmental pollutant, tetrachloro dibenzo dioxin (TCDD) is known to illicit the cognitive disability and motor dysfunction in the developing brain. TCDD induced effects leading to neurodevelopmental and neurobehavioral deficit...
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Myocardial injury occurs earlier than myocardial inflammation in acute experimental viral myocarditis

Lim BK, Shin JO, Choe SC, Choi SW, Jeong JO, Seong IW, Kim DK, Jeon ES

  • KMID: 1033101
  • Exp Mol Med.
  • 2005 Feb;37(1):51-57.
Endomyocardial biopsy often fails to show myocardial inflammation for patients with clinically suspected myocarditis. The serum isoforms of troponin T (cTnT) level is a very sensitive marker of myocardial injury...
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Leukotriene B4 pathway regulates the fate of the hematopoietic stem cells

Chung JW, Kim GY, Mun YC, Ahn JY, Seong CM, Kim JH

  • KMID: 1033100
  • Exp Mol Med.
  • 2005 Feb;37(1):45-50.
Leukotriene B4(LTB4), derived from arachidonic acid, is a potent chemotactic agent and activating factor for hematopoietic cells. In addition to host defense in vivo, several eicosanoids have been reported to...
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Efficient gene delivery in differentiated human embryonic stem cells

Kim JH, Do HJ, Choi SJ, Cho HJ, Park KH, Yang HM, Lee SH, Kim DK, Kwack K, Oh SK, Moon SY, Cha KY, Chung HM

  • KMID: 1033099
  • Exp Mol Med.
  • 2005 Feb;37(1):36-44.
Human embryonic stem (hES) cells are capable of differentiating into pluralistic cell types, however, spontaneous differentiation generally gives rise to a limited number of specific differentiated cell types and a...
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Monocrotaline-induced pulmonary hypertension correlates with upregulation of connective tissue growth factor expression in the lung

Lee YS, Byun J, Kim JA, Lee JS, Kim KL, Suh YL, Kim JM, Jang HS, Lee JY, Shin IS, Suh W, Jeon ES, Kim DK

  • KMID: 1033098
  • Exp Mol Med.
  • 2005 Feb;37(1):27-35.
Pulmonary hypertension (PH) is characterized by structural and functional changes in the lung including proliferation of vascular smooth muscle cells (VSMCs) and excessive collagen synthesis. Although connective tissue growth factor...
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NF-kappa B decoy potentiates the effects of radiation on vascular smooth muscle cells by enhancing apoptosis

Zhang SY, Park KW, Oh S, Cho HJ, Cho HJ, Park JS, Cho YS, Koo BK, Chae IH, Choi DJ, Kim HS, Lee MM

  • KMID: 1033097
  • Exp Mol Med.
  • 2005 Feb;37(1):18-26.
NF-kappa B promotes cell survival against external stress such as radiation. We examined whether NF-kappa B decoy transfection enhances the antiproliferative effects of radiation on vascular smooth muscle cells (VSMCs)...
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Genetic polymorphism of CYP17 and breast cancer risk in Korean women

Shin MH, Lee KM, Yang JH, Nam SJ, Kim JW, Yoo KY, Park SK, Noh DY, Ahn SH, Kim B, Kang D

  • KMID: 1033096
  • Exp Mol Med.
  • 2005 Feb;37(1):11-17.
CYP17 gene is involved in steroidogenesis and steroid metabolism. Epidemiologic results on the association between the CYP17 polymorphism and breast cancer risk have been inconsistent. We examined the association between...
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Proteomic applications of surface plasmon resonance biosensors: analysis of protein arrays

Yuk JS, Ha KS

  • KMID: 1033095
  • Exp Mol Med.
  • 2005 Feb;37(1):1-10.
Proteomics is one of the most important issues in the post-genomic area, because it can greatly contribute to identifying protein biomarkers for disease diagnosis and drug screening. Protein array is...
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