- Growth impairment of primary chondrocyte cells by serum of rats with chronic renal failure
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Mak RH, Chang SL, Pak YK
- KMID: 1097106
- Exp Mol Med.
- 2004 Jun;36(3):243-250.
Insulin-like growth factor (IGF)/IGF binding protein (IGFBP) abnormalities may be important in the pathogenesis of growth failure in chronic renal failure (CRF). We induced experimental CRF by 5/6 nephrectomy in... -
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- Calcium cycling proteins in heartfailure, cardiomyopathy and arrhythmias
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Minamisawa S, Sato Y, Cho MC
- KMID: 1097100
- Exp Mol Med.
- 2004 Jun;36(3):193-203.
A growing body of evidence, including studies using genetically engineered mouse models, has shown that Ca2+ cycling and Ca2+ -dependent signaling pathways play a pivotal role in cardiac hypertrophy and... -
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- Molecular variations in Th1-specific cell surface gene Tim-3
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Chae SC, Song JH, Pounsambath P, Yuan HY, Lee JH, Kim JJ, Lee YC, Chung HT
- KMID: 1097110
- Exp Mol Med.
- 2004 Jun;36(3):274-278.
The family of T-cell immunoglobulin domain and mucin domain (TIM) proteins is identified to be expressed on T cells. A member of Tim family, Tim-3 (T cell immunoglobulin mucin 3)... -
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- Real-Time PCR analysis of af4 and dek genes expression in acute promyelocytic leukemiat (15;17)patients
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Savli H, Sirma S, Nagy B, Aktan M, Dincol G, Salcioglu , Sarper N, Ozbek U
- KMID: 1097111
- Exp Mol Med.
- 2004 Jun;36(3):279-282.
Among several newly identified oncogenes, dek and af4 are attractive targets for researchers interested with leukemia. In this study quantitative Real-Time RT-PCR technique was used to define alterations in expression... -
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- Interleukin-1beta stimulates matrix metalloproteinase-2 expression via a prostaglandin E2-dependent mechanism in human chondrocytes
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Choi YA, Lee DJ, Lim HK, Jeong JH, Sonn JK, Kang SS, Baek SH
- KMID: 1097104
- Exp Mol Med.
- 2004 Jun;36(3):226-232.
IL-1beta is known promote cyclooxygenase-2 (COX- 2) and matrix metalloproteinase-2 (MMP-2) expression. This study focuses on the characterization of the signaling cascade associated with IL-1beta-induced matrix metalloproteinase-2 (MMP- 2) regulation... -
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- Involvement of throm box aneA2 and tyrosine kinase in the synergistic interaction of platelet activating factor and calcium ionophore A23187 in human platelet aggregation
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Rasheed H, Saeed SA
- KMID: 1097103
- Exp Mol Med.
- 2004 Jun;36(3):220-225.
The present study was carried out to examine the mechanisms of the synergistic interaction of PAF and A23187 mediated platelet aggregation. We found that platelet aggregation mediated by subthreshold concentrations... -
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- Gene expression in uremic left ventricular hypertrophy: effects of hypertension andanemia
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Mak RH, Chang SL, Draksharapu A, Pak YK
- KMID: 1097107
- Exp Mol Med.
- 2004 Jun;36(3):251-258.
Hypertension and anemia may be causes of left ventricular hypertrophy (LVH) in uremia but the molecular mechanism is not known. Uremia was induced in male Spraugue Dawley rats by 5/6... -
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- Molecular technology and the recombinant TSH have changed diagnostics of thyroid carcinoma with positive I-131 whole body scan but low serum thyroglobulin
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Montella L, Caraglia M, Abbruzzese A, Soricelli , Prete SD, Squame G, Salvatore
- KMID: 1097109
- Exp Mol Med.
- 2004 Jun;36(3):268-273.
The early detection of recurrent differentiated thyroid carcinoma (DTC) cells in the post surgery DTC patients relies on the sensitivity of measuring both the level of thyroglobulin (Tg) and 131-Iodine... -
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- Human beta-defensin 2 is induced by interleukin-1b in the cornealepithelial cells
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Shin JS, Kim CW, Kwon YS, Kim JC
- KMID: 1097101
- Exp Mol Med.
- 2004 Jun;36(3):204-210.
Mammalian epithelia produce the various antimicrobial peptides against the bacterial or viral infection, thereby acting as the active immune modulators in the innate immunity. In this study, we examined the... -
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- Association of DNA-dependent protein kinase with hypoxia induciblefactor-1 and its implication inresistance to anticancer drugs in hypoxic tum or cells
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Um JH, Kang CD, Bae JH, Shin GG, Kim DW, Kim DW, Chung BS, Kim SH
- KMID: 1097105
- Exp Mol Med.
- 2004 Jun;36(3):233-242.
Tumor hypoxia contributes to the progression of a malignant phenotype and resistance to ionizing radiation and anticancer drug therapy. Many of these effects in hypoxic tumor cells are mediated by... -
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- Beta ig-h3 promotes renal proximal tubular epithelial cell adhesion, migration and proliferation through the interaction with alpha3beta1 integrin
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Park SW, Bae JS, Kim KS, Park SH, Lee BH, Choi JY, Park JY, Ha SW, Kim YL, Kwon TH, Kim IS, Park RW
- KMID: 1097102
- Exp Mol Med.
- 2004 Jun;36(3):211-219.
Betaig-h3 (betaig-h3) is a secretory protein composed of fasciclin I-like repeats containing sequences that allows binding of integrins and glycosaminoglycans in vivo. Expression of betaig-h3 is responsive to TGF-beta and... -
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- Paradoxical effects of elastase inhibitor guamerin on the tissue repair of two different wound models: sealed cut and exposed tongue wounds
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Lee SK, Lee SS, Song IS, Kim YS, Park YW, Joo JY, Um HS, Kim JW, Kim KY, Choi SJ, Jung KH, Chung SI
- KMID: 1097108
- Exp Mol Med.
- 2004 Jun;36(3):259-267.
Innate elastase inhibitors are known to be putatively involved in the regulation of tissue inflammation by inhibiting polymorphonuclear leukocyte (PMN) derived proteinases. The aim of this study was to evaluate... -
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