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Soluble factor from tumor cells induces heme oxygenase-1 by a nitric oxide-independent mechanism in murine peritoneal macrophages

Kim SW, Oh HM, Kim BS, Chung HT, Han WC, Kim EC, Kim TH, Seo GS, Lyou JH, Nah YH, Jung JC, Choi SC, Jun CD

  • KMID: 1088658
  • Exp Mol Med.
  • 2003 Feb;35(1):53-59.
Tumor target-derived soluble secretary factor has been known to influence macrophage activation to induce nitric oxide (NO) production. Since heme oxigenase-1 (HO-1) is induced by a variety of conditions associated...
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Five subtypes of muscarinic receptors are expressed in gastric smooth muscles of guinea pig

So I, Yang DK, Kim HJ, Min KW, Kang TM, Kim SJ, Kim KW, Park KH, Jeon JH, Choi KH, Kim IG

  • KMID: 1088657
  • Exp Mol Med.
  • 2003 Feb;35(1):46-52.
Muscarinic receptors play key roles in the control of gastrointestinal smooth muscle activity. However, specific physiological functions of each subtype remain to be determined. In this study, the nonselective cation...
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Anti-apoptotic role of phospholipase D isozymes in the glutamate-induced cell death

Kim KO, Lee KH, Kim YH, Park SK, Han JS

  • KMID: 1088656
  • Exp Mol Med.
  • 2003 Feb;35(1):38-45.
Abstract Phospholipase D (PLD) plays an important role as an effector in a variety of physiological processes that reveal it to be a member of the signal transducing phospholipases. Recently,...
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Metastasis-suppressor KAI1/CD82 induces homotypic aggregation of human prostate cancer cells through Src-dependent pathway

Jee B, Jin K, Hahn JH, Song HG, Lee H

  • KMID: 1088655
  • Exp Mol Med.
  • 2003 Feb;35(1):30-37.
To investigate the functional role of KAI1/CD82, a metastasis suppressor for human prostate cancer, in the regulation of homotypic cell adhesion, we transfected KAI1 cDNA into DU 145 human prostate...
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Acetyl-CoA carboxylase beta expression mediated by MyoD and muscle regulatory factor 4 is differentially affected by retinoic acid receptor and retinoid X receptor

Kim JY, Lee JJ, Kim KS

  • KMID: 1088654
  • Exp Mol Med.
  • 2003 Feb;35(1):23-29.
Mammals have two major isoforms of acetyl-CoA carboxyase (ACC). The 275 kDa beta-form (ACC beta) is predominantly in heart and skeletal muscle while the 265 kDa alpha-form (ACC alpha) is...
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Enzymatic method for assaying calcium in serum with Ca++-ATPase

Javed HM, Michelangeli F

  • KMID: 1088653
  • Exp Mol Med.
  • 2003 Feb;35(1):17-22.
A kinetic assay for total calcium in serum was developed which is based on the activation of Ca++-ATPase by free Ca++ [Ca++]f maintained by EGTA in the reaction mixture. The...
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Involvement of tumor necrosis factor receptor superfamily (TNFRSF) members in the pathogenesis of inflammatory diseases

Kwon B, Kim BS, Cho HR, Park JE, Kwon BS

  • KMID: 1088652
  • Exp Mol Med.
  • 2003 Feb;35(1):8-16.
Current therapies for autoimmune diseases are not cures but merely palliatives, aimed at reducing symptoms. For the most part, these treatments provide nonspecific suppression of the immune system and thus...
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Conjugation and deconjugation of ubiquitin regulating the destiny of proteins

Baek KH

  • KMID: 1088651
  • Exp Mol Med.
  • 2003 Feb;35(1):1-7.
The homeostasis for a number of cellular proteins is regulated by not only phosphorylation and dephosphorylation, but also ubiquitination and deubiquitination. A number of proteins involved in the degradation of...
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