- Prevention of liver cancer: basic and clinical aspects
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Moriwaki H
- KMID: 755202
- Exp Mol Med.
- 2002 Nov;34(5):319-325.
Cancer prevention is a challenging project both in the basic and clinical medicine. In particular, prevention of liver cancer is the most urgent task in countries where the incidence of... -
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- C/EBP binding activity to site F of the rat GLUT2 glucose transporter gene promoter is attenuated by c-Jun in vitro
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Kim JW, Ahn YH
- KMID: 755211
- Exp Mol Med.
- 2002 Nov;34(5):379-384.
The expression of the GLUT2 glucose transporter gene in liver is suppressed in cultured hepatoma cell lines and primary cultured hepatocytes. Earlier report showed that CCAAT/enhancer binding protein (C/EBP) regulates... -
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- Macrophage colony-stimulating factor promotes the survival of osteoclast precursors by up-regulating Bcl-XL
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Woo KM, Kim HM, Ko JS
- KMID: 755205
- Exp Mol Med.
- 2002 Nov;34(5):340-346.
Macrophage colony-stimulating factor (M-CSF) is known as one of the factors essential for osteoclast development. In the present study, we examined effects of M-CSF on the apoptotic pathway of osteoclast... -
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- Proteomic analysis of the cellular proteins induced by adaptive concentrations of hydrogen peroxide in human U937 cells
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Seong JK, Kim DK, Choi KH, Oh SH, Kim KS, Lee SS, Um HD
- KMID: 755210
- Exp Mol Med.
- 2002 Nov;34(5):374-378.
When cells are first exposed to low levels of oxidative stress, they develop a resistance to a subsequent challenge of the same stress, even at higher levels. Although some protein(s)... -
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- Inhibition of BETA2/NeuroD by Id2
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Ghil SH, Jeon YJ, Suh-Kim H
- KMID: 755209
- Exp Mol Med.
- 2002 Nov;34(5):367-373.
Id (Inhibitor of Differentiation) proteins belong to a family of transcriptional modulators that are characterized by a helix loop helix (HLH) region but lack the basic amino acid domain. Id... -
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- Comparative binding of antitumor drugs to DNA containing the telomere repeat sequence
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Suh D, Oh YK, Ahn BC, Hur MW, Kim HJ, Lee MH, Joo HS, Auh CK
- KMID: 755203
- Exp Mol Med.
- 2002 Nov;34(5):326-331.
Telomeres are the ends of the linear chromosomes of eukaryotes and consist of tandem GT-rich repeats in telomere sequence i.e. 500-3000 repeats of 5'-TTAGGG-3' in human somatic cells, which are... -
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- Osteoprotegerin is present on the membrane of osteoclasts isolated from mouse long bones
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Woo KM, Choi Y, Ko SH, Ko JS, Oh KO, Kim KK
- KMID: 755206
- Exp Mol Med.
- 2002 Nov;34(5):347-352.
Osteoprotegerin (OPG), a member of the tumor necrosis factor receptor superfamily, is known to inhibit osteoclastogenesis by acting as a soluble decoy receptor for the receptor activator of NF-kB ligand... -
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- Effects of Val34Leu and Val35Leu polymorphism on the enzyme activity of the coagulation factor XIII-A
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Lee IH, Chung SI, Lee SY
- KMID: 755212
- Exp Mol Med.
- 2002 Nov;34(5):385-390.
Change in fibrin stabilizing activity of factor XIII A subunit (FXIII-A) caused by a specific mutation, Val34Leu, is recently implicated to incidences of pathophysiology of thrombosis. In an effort to... -
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- Dual effect of oxidative stress on NF-kappaB activation in HeLa cells
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Byun MS, Jeon KI, Choi JW, Shim JY, Jue DM
- KMID: 755204
- Exp Mol Med.
- 2002 Nov;34(5):332-339.
Reactive oxygen species (ROS) has been implicated as an inducer of NF-kappaB activity in numbers of cell types where exposure of cells to ROS such as H2O2 leads to NF-kappaB... -
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- Retinoic acid inhibits inducible nitric oxide synthase expression in 3T3-L1 adipocytes
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Yang JY, Koo BS, Kang MK, Rho HW, Sohn HS, Jhee EC, Park JW
- KMID: 755207
- Exp Mol Med.
- 2002 Nov;34(5):353-360.
The present study was undertaken to explore whether retinoids, which are known to have immunomodulatory actions, could attenuate tumor necrosis factor-alpha (TNF)-stimulated inducible nitric oxide synthase (iNOS) expression in 3T3-L1... -
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- Changes in expression of cell cycle regulators after G1 progression upon repetitive thioacetamide treatment in rat liver
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Hong SH, Lee GD, Chung JY, Cho KS, Park SH, Kim IH, Jeong JS
- KMID: 755208
- Exp Mol Med.
- 2002 Nov;34(5):361-366.
Repetitive low dose thioacetamide (TA) treatment of hepatocytes was found to induce cells in G2 arrest. In the present study, an attempt was made to investigate alterations in expression of... -
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