- Differential expression of two stress-inducible hsp70 genes by various stressors
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Lee JS, Seo JS
- KMID: 1081462
- Exp Mol Med.
- 2002 May;34(2):131-136.
Inducible HSP70s encoded by two almost identical hsp70 genes, known as hsp70.1 and hsp70.3 are located in a tandem array on mouse chromosome 17. Duplication of this gene has been... -
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- Effects of estrogen receptor and estrogen on the chromatin structure in estrogen receptor stable transfectants
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Lee YJ, Lim WC, Jin YH, Lee SK
- KMID: 1081457
- Exp Mol Med.
- 2002 May;34(2):95-99.
The estrogen receptor (ER), a member of the nuclear hormone receptor superfamily recruits coactivators that modify local chromatin structure. Here we investigated the effect of the estrogen receptor and estrogen... -
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- Antioxidant activity of extracts from Euryale ferox seed
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Lee SE, Ju EM, Kim JH
- KMID: 1081458
- Exp Mol Med.
- 2002 May;34(2):100-106.
Euryale ferox has been widely used in traditional oriental medicine to treat a variety of illness. However, very little is known about the cellular actions by which this plant mediates... -
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- Quantitative measurement of serum allergen-specific IgE on protein chip
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Kim TE, Park SW, Cho NY, Choi SY, Yong TS, Nahm BH, Lee S, Noh G
- KMID: 1081465
- Exp Mol Med.
- 2002 May;34(2):152-158.
Type I allergy is an immunoglobulin E (IgE)-mediated hypersensitivity disease inflicting more than quarter of the world population. In order to identify allergen sources, skin provocation test and IgE serology... -
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- Inhibitory action of bisphosphonates on bone resorption does not involve the regulation of RANKL and OPG expression
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Kim YH, Kim GS, Baek JH
- KMID: 1081464
- Exp Mol Med.
- 2002 May;34(2):145-151.
The mechanism of inhibitory action of bisphosphonates on bone resorption is not fully elucidated. Osteoclast formation and activity are regulated by osteoblast-derived factors such as the osteoclast differentiating factor, receptor... -
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- Induction of Bis, a Bcl-2-binding protein, in reactive astrocytes of the rat hippocampus following kainic acid-induced seizure
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Lee MY, Kim SY, Choi JS, Choi YS, Jeon MH, Lee JH, Kim IK, Lee JH
- KMID: 1081467
- Exp Mol Med.
- 2002 May;34(2):167-171.
The expression of Bis (also called Bag-3), a Bcl-2-binding protein, was investigated in the rat kainic acid (KA) model of temporal lobe epilepsy. Western blot analysis showed a significant increase... -
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- Basic fibroblast growth factor-induced translocation of p21-activated kinase to the membrane is independent of phospholipase C-gamma1 in the differentiation of PC12 cells
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Shin KS, Shin EY, Lee CS, Quan SH, Woo KN, Soung NK, Kwak SJ, Kim SR, Kim EG
- KMID: 1081468
- Exp Mol Med.
- 2002 May;34(2):172-176.
p21-activated kinase (PAK) targeting to the plasma membrane is essential for PC12 cell neurite outgrowth. Phospholipase C-gamma1 (PLC-gamma1) can mediate the PAK translocation in response to growth factors, since PLC-gamma1... -
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- HPV E6 antisense induces apoptosis in CaSki cells via suppression of E6 splicing
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Cho CW, Poo H, Cho YS, Cho MC, Lee KA, Lee SJ, Park SN, Kim IK, Jung YK, Choe YK, Yeom YI, Choe IS, Yoon DY
- KMID: 1081466
- Exp Mol Med.
- 2002 May;34(2):159-166.
Cervical cancer is known to be highly associated with viral oncogene E6 and E7 of human papilloma virus. Down-regulation of oncogene expression by antisense-based gene therapy has been extensively studied.... -
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- Effects of high taurocholate load on activities of hepatic alcohol metabolizing enzymes
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Kim YH, Shin MJ
- KMID: 1081461
- Exp Mol Med.
- 2002 May;34(2):123-130.
Membrane-associated cytotoxicity induced by hydrophobic bile salts is a major contributing factor leading to liver diseases. Administration of ursodeoxycholate reduces serum liver enzymes in chronic liver diseases but the nature... -
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- Induction of hepatic inducible nitric oxide synthase by cholesterol in vivo and in vitro
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Kim JW, Kang KW, Oh GT, Song J, Kim ND, Pak YK
- KMID: 1081463
- Exp Mol Med.
- 2002 May;34(2):137-144.
Cholesterol-rich diet impairs endothelial NO synthase (eNOS) and enhances inducible NOS (iNOS) expression. In this study, we investigated effects of cholesterol on iNOS expression in high-fat-fed rat models, HepG2 and... -
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- The effect of telomerase expression on the escape from M2 crisis in virus-transformed human retinal pigment epithelial cells
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Park JK, Kim BH, Han YS, Park IK
- KMID: 1081459
- Exp Mol Med.
- 2002 May;34(2):107-113.
Transformation with viral oncogene extends the lifespan of normal cells beyond replicative senescence called M1, but most of them eventually succumb to second crisis called M2 when telomeres become critically... -
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- Human hepatocellular carcinoma cells resist to TRAIL-induced apoptosis, and the resistance is abolished by cisplatin
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Shin EC, Seong YR, Kim CH, Kim H, Ahn YS, Kim K, Kim SJ, Hong SS, Park JH
- KMID: 1081460
- Exp Mol Med.
- 2002 May;34(2):114-122.
TNF-related apoptosis-inducing ligand (TRAIL), a member of the TNF family, selectively induce apoptosis in various transformed cell lines but not in almost-normal tissues. It is regulated by 2 death receptors,... -
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