- Cholesterol induce oligomerization of Vibrio vulnificus cytolysin specifically.
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Kim BS, Kim JS
- KMID: 1380232
- Exp Mol Med.
- 2002 Jul;34(3):239-242.
Vibrio vulnificus cytolysin (VVC) has been implicated as one of the important virulence determinants of V. vulnificus that causes serious septicemia and wound infection. An attempt was made to investigate... -
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- Expression and characterization of a mutant recombinant blood coagulation factor VIII (rFVIII (m)).
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Oh SH, Cho SY, Jin HS, Jeong DL, Jung SG, Oh KH
- KMID: 1380231
- Exp Mol Med.
- 2002 Jul;34(3):233-238.
In an earlier study, a site directed mutant rFVIII (rFVIII(m), Arg(336) -> Gln(336)) expressed in baculovirus-insect cell (Sf9) system was found to sustain high level activity during incubation at 37... -
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- Differential effects of Fas cross-linking on phospholipase D activation and related lipid metabolism in Fas-resistant A20 cells.
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Lim SY, Lee SC, Shin IC, Han JS
- KMID: 1380228
- Exp Mol Med.
- 2002 Jul;34(3):201-210.
A20 murine lymphoma cells undergoing Fas-mediated apoptosis showed increase in the activity of phospholipase D (PLD), which is involved in proliferative or mitogenic cellular responses. Using A20 cell lines that... -
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- Structural basis for inhibition of protein tyrosine phosphatases by Keggin compounds phosphomolybdate and phosphotungstate.
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Heo YS, Ryu JM, Park SM, Park JH, Lee HC, Hwang KY, Kim JS
- KMID: 1380229
- Exp Mol Med.
- 2002 Jul;34(3):211-223.
Protein-tyrosine phosphatases (PTPs) constitute a family of receptor-like, and cytoplasmic enzymes, which catalyze the dephosphorylation of phosphotyrosine residues in a variety of receptors and signaling molecules. Together with protein tyrosine... -
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- Effect of local background intensities in the normalization of cDNA microarray data with a skewed expression profiles.
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KIm JH, Shin DM, Lee YS
- KMID: 1380230
- Exp Mol Med.
- 2002 Jul;34(3):224-232.
Normalization of the data of cDNA microarray is an obligatory step during microarray experiments due to the relatively frequent non-specific errors. Generally, normalization of microarray data is based on the... -
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- Sox-4 is a positive regulator of Hep3B and HepG2 cells' apoptosis induced by prostaglandin (PG)A2 and 12-PGJ2.
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Ahn SG, Kim HS, Jeong SW, Kim BE, Rhim HS, Shim JY, Kim JW, Lee JH, Kim IK
- KMID: 1380233
- Exp Mol Med.
- 2002 Jul;34(3):243-249.
We reported earlier that expression of Sox-4 was found to be elevated during prostaglandin (PG) A2 and delta(12)-PGJ(12) induced apoptosis in human hepatocarcinoma Hep3B cells. In this study, the role... -
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- The effect of telomerase expression on the escape from M2 crisis in virus-transformed human retinal pigment epithelial cells.
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Hwang JH, Park MI, Hwang YY, Yoo HJ, Mardon HJ
- KMID: 1380227
- Exp Mol Med.
- 2002 Jul;34(3):194-200.
Integrins are heterodimeric glycoproteins that have been found to undergo dynamic temporal and spatial changes in the endometrium during the menstrual cycle and in early pregnancy. Specificity of integrins is... -
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- Functional involvement of src and focal adhesion kinase in a CD99 splice variant-induced motility of human breast cancer cells.
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Lee HJ, Kim ES, Jee BE, Hahn JH, Han KH, Jung KC, Park SH, Lee HS
- KMID: 1380225
- Exp Mol Med.
- 2002 Jul;34(3):177-183.
Earlier report showed that expression of a splice variant of CD99 transmembrane protein increases invasive ability of human breast cancer cells. Cell motility was also significantly enhanced by the CD99... -
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- Role of Ca(2+) in diallyI disulfide-induced apoptotic cell death of HCT-15 cells.
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Park EK, Kwon KB, Park KI, Park BH, Jhee EC
- KMID: 1380234
- Exp Mol Med.
- 2002 Jul;34(3):250-257.
Diallyl disulfide (DADS) induced apoptosis through the caspase-3 dependent pathway in leukemia cells was earlier reported from this laboratory. In this study, we investigated the involvement of Ca(2+) in DADS-induced... -
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- Genome-wide expression profiling of 8-chloroadenosine- and 8-chloro-cAMP-treated human neuroblastoma cells using radioactive human cDNA microarray.
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Park GH, Choe JG, Choo HJ, Park YG, Sohn JW, Kim MK
- KMID: 1380226
- Exp Mol Med.
- 2002 Jul;34(3):184-193.
Previous reports raised question as to whether 8-chloro-cyclic adenosine 3,5-monophosphate (8-Cl-cAMP) is a prodrug for its metabolite, 8-Cl-adenosine which exerts growth inhibition in a broad spectrum of cancer cells. The... -
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