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Regulation of chicken protein tyrosine phosphatase 1 and human protein tyrosine phosphatase 1B activity by casein kinase II- and p56lck-mediated phosphorylation

Kang KR, Kim CW

  • KMID: 927134
  • Exp Mol Med.
  • 2000 Mar;32(1):47-51.
Protein tyrosine phosphorylation and dephosphorylation are important in the regulation of cell proliferation and signaling cascade. In order to examine whether phosphatase activity of CPTP1 and HPTP1B, typical nontransmembrane protein...
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Regulation of bcl-2 family in hydrogen peroxide-induced apoptosis in human leukemia HL-60 cells

Lee JE, Sohn JW, Lee JH, Lee KC, Son CS, Tockgo YC

  • KMID: 927133
  • Exp Mol Med.
  • 2000 Mar;32(1):42-46.
Numerous types of cells have been shown to undergo apoptosis when exposed to oxidant agent such as hydrogen peroxide. In order to understand the functional relationship between the anti- and...
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Detection of cryptic Y chromosome mosaicism by coamplification PCR with archived cytogenetic slides of suspected Turner syndrome

Kim JW, Cho EH, Kim YM, Kim JM, Han JY, Park SY

  • KMID: 927132
  • Exp Mol Med.
  • 2000 Mar;32(1):38-41.
Turner syndrome is one of the most common cytogenetic abnormalities. It is known that the Y chromosome or Y derived material is present in 6-9% of TS patient and it...
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Dedifferentiation of conditionally immortalized hepatocytes with long-term in vitro passage

Kim BH, Sung SR, Choi EH, Kim YI, Kim KJ, Dong SH, Kim HJ, Chang YW, Lee JI, Chang R

  • KMID: 927131
  • Exp Mol Med.
  • 2000 Mar;32(1):29-37.
The rat hepatocytes were immortalized using a temperature-sensitive mutant of SV40 large T antigen (tsT) to develop as a possible substitute for primary hepatocytes. Four rat hepatocyte lines that have...
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Enhanced induction of Bax gene expression in H460 and H1299 cells with the combined treatment of cisplatin and adenovirus mediated wt-p53 gene transfer

Choi JH, Ahn KS, Kim JG, Hong YS

  • KMID: 927130
  • Exp Mol Med.
  • 2000 Mar;32(1):23-28.
Cytotoxic effect of either cisplatin or p53 gene transfection of lung cancer cells may be different depending on the p53 status of cells. We investigated cytotoxic effects on the combined...
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Cross-linking of CD4 induces cytoskeletal association of CD4 and p56lck

Ha-Lee YM, Lee YS, Kim YK, Sohn JW

  • KMID: 927129
  • Exp Mol Med.
  • 2000 Mar;32(1):18-22.
A membrane glycoprotein CD4 functions as a co-receptor of a T lymphocyte. The co-receptor function has been attributed to a protein tyrosine kinase, p56lck, which is activated upon CD4 binding...
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Protective mechanism of glucose against alloxan-induced beta-cell damage: pivotal role of ATP

Rho HW, Lee JN, Kim HR, Park BH, Park JW

  • KMID: 927128
  • Exp Mol Med.
  • 2000 Mar;32(1):12-17.
Glucose prevents the development of diabetes induced by alloxan. In the present study, the protective mechanism of glucose against alloxan-induced beta-cell damage was investigated using HIT-T 15 cell, a Syrian...
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The new genotypic human calicivirus isolated in Seoul

Han DP, Lee HW, Sohn JH, Yeh BI, Choi JW, Kim HW

  • KMID: 927127
  • Exp Mol Med.
  • 2000 Mar;32(1):6-11.
A new type of human calicivirus (HuCV) showing the classic cup-shaped surface morphology was identified in the stool sample from a child with symptoms of acute gastroenteritis in Seoul, Korea...
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Quantitative characterization of reversible macromolecular associations via sedimentation equilibrium: an introduction

Minton AP

  • KMID: 927126
  • Exp Mol Med.
  • 2000 Mar;32(1):1-5.
The measurement and analysis of sedimentation equilibrium provides one of the most powerful and widely applicable methods for the characterization of reversible associations of macromolecules in solution. Recent developments...
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