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Activation of monocytes, T-lymphocytes and plasma inflammatory markers in angina patients

Lee WH, Lee Y, Kim JR, Chu JA, Lee SY, Jung JO, Kim JS, Kim S, Seo JD, Rhee SS, Park JE

  • KMID: 755045
  • Exp Mol Med.
  • 1999 Sep;31(3):159-164.
Inflammation and activation of immune cells have important roles in the pathogenesis of atherosclerosis. We analyzed the plasma levels of inflammatory markers and the degree of activation of peripheral blood monocytes and T-lymphocytes...
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Cooperative binding interaction of ethidium with allosteric DNA

Suh D

  • KMID: 755044
  • Exp Mol Med.
  • 1999 Sep;31(3):151-158.
The specific association of drugs with deoxyoligonucleotides, containing a B-Z junction between left-handed Z-DNA and right-handed B-DNA, was examined by fluorescence and circular dichroism (CD) technique. Ethidium was chosen for a simple DNA...
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Effect of ceramide on apoptosis and phospholipase D activity in FRTL-5 thyroid cells

Park BJ, Kim JH, Han JS, Jung PM

  • KMID: 755043
  • Exp Mol Med.
  • 1999 Sep;31(3):142-150.
Ceramide, a product of sphingomyelin hydrolysis, is now recognized as an intracellular lipid messenger, which mediates the effects of extracellular agents on cellular growth, differentiation and apoptosis. Recently, ceramide has been implicated in...
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Cytolytic activity of mitogen activated old and young mouse spleen cells against tumor target cells expressing high or low levels of Fas antigen

Saxena RK, Adler WH

  • KMID: 755042
  • Exp Mol Med.
  • 1999 Sep;31(3):137-141.
Sensitivity of Fas expressing tumor cells (high levels in Hut78 & Jurkat; low levels in P815) toward the cytotoxic Con-A (5 microg/ml) activated spleen cells from young (12 to 16 week old...
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Prenatal detection of de novo inversion of chromosome 9 with duplicated heterochromatic region and postnatal follow-up

Kim JJ, Rhee HS, Chung YT, Park SY, Choi SK

  • KMID: 755041
  • Exp Mol Med.
  • 1999 Sep;31(3):134-136.
We report the first de novo case of a heterochromatic duplication on the long arm of the chromosome 9, which then was pericentrically inverted at p11q13. This condition was detected prenatally and...
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TGF-beta1 inhibition of apoptosis through the transcriptional up-regulation of Bcl-X(L) in human monocytic leukemia U937 cells

Lee JH, Park BJ, Park JH, Yang MH, Chi SG

  • KMID: 755040
  • Exp Mol Med.
  • 1999 Sep;31(3):126-133.
To characterize the TGF-beta1 response of monocytic leukemia cells, we analyzed the effects of TGF-beta1 on cell proliferation, differentiation, and apoptosis of human monoblastic U937 cells. Treatment of cells with TGF-beta1 in...
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A radioimmunoassay method for detection of DNA based on chemical immobilization of anti-DNA antibody

Yoo SK, Yoon MO, Park UJ, Han HS, Kim JH, Hwang HJ

  • KMID: 755039
  • Exp Mol Med.
  • 1999 Sep;31(3):122-125.
High selectivity provided by biomolecules such as antibodies and enzymes has been exploited during the last two decades for development of biosensors. Of particular importance are efficient immobilization methods for biomolecules in order...
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Immune mechanisms of Theiler's virus-induced demyelination

Kim BS, Palna JP

  • KMID: 755038
  • Exp Mol Med.
  • 1999 Sep;31(3):115-121.
No abstract available.
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