- The S-genomic RNA of Hantaan virus contains only two trinucleotide repeats at its 5' end and the 3' end of 3'-specific mRNA is truncated and lacks poly-A tail
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Dobbs M, Jin MR, Kang CY
- KMID: 2128630
- Exp Mol Med.
- 1997 Mar;29(1):81-83.
No abstract available. -
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- Purification of thrombospondin receptor (CD36) from human platelet membrane
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Kim JH, Suk KH, Park NY, Kim SH
- KMID: 2128623
- Exp Mol Med.
- 1997 Mar;29(1):31-34.
Thrombospondin receptor (CD36) has been recently identified in platelets and various cell lines as the receptor for thrombospondin, an adhesive protein required for irreversible aggregation of platelets as well as... -
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- Purification and characterization of lactate dehydrogenase from Varanus liver
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Javed MH M, Azimuddin , Hussain AN, Ahmed A, Ishaq M
- KMID: 2128622
- Exp Mol Med.
- 1997 Mar;29(1):25-30.
Lactate dehydrogenase was purified 21-fold from liver of Varanus bengalensis using colchicine-sepharose column chromatography. The crude enzyme showed two isoenzymes (LDH-5 and LDH-4) by agarose gel electrophoresis (AGE). The purified... -
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- Cell cycle checkpoint control
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Murakami H, Okayama H
- KMID: 2128619
- Exp Mol Med.
- 1997 Mar;29(1):1-11.
Genetic instability is considered to be a major driving force of malignancy of cancer cells, and at least some of cancer-associated genetic instability is known to be caused by defects... -
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- Modulation by aspartate of ischemia/reperfusion-induced oxidative stress in rat liver
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Park YC, Oh SI, Park YH, Park SC
- KMID: 2128621
- Exp Mol Med.
- 1997 Mar;29(1):19-23.
Ischemia-reperfusion injury is related with oxygen free radicals; a reason which has been suggested for this is the conversion of xanthine dehydrogenase (XDH) into xanthine oxidase (XO). In the present... -
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- The parathyroid hormone-2 receptor: Current status
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Usdin TB
- KMID: 2128620
- Exp Mol Med.
- 1997 Mar;29(1):13-17.
G-protein coupled receptors form a large superfamily of plasma membrane proteins which serve a variety of signal transduction roles. New receptors continue to be identified. Based on sequence homology the... -
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- Retroviral-mediated IL-12 gene therapy for advanced murine tumors
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Kim SH, An CS, Tahara H, Park CH, Lotze MT, Robbins PD, Kim SY
- KMID: 2128626
- Exp Mol Med.
- 1997 Mar;29(1):53-58.
Interleukin 12 (IL-12), a heterodimeric cytokine, promotes an effective antitumor response against tumors of various histological types when delivered systemically as a protein or locally by gene transfer. We investigated... -
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- Effect of high glucose on synthesis and gene expression of collagen and fibronectin in cultured vascular smooth muscle cells
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Ha SW, Ha SW, Seo YK, Kim JG, Kim IS, Sohn KY, Lee BH, Kim BW
- KMID: 2128627
- Exp Mol Med.
- 1997 Mar;29(1):59-64.
Diabetes mellitus is an important risk factor of atherosclerosis. Although the mechanism for accelerated atherosclerotic disease in diabetes mellitus is not clear, extracellular matrix formation by vascular smooth muscle cells... -
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- Membrane activator of the 72 kDa type IV collagenase in malignant breast carcinoma patients: Expression of membrane-type 1-matrix metalloproteinase (MT1-MMP)
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Chai KJ, Lee HJ, Lee SJ, Lee KS
- KMID: 2128629
- Exp Mol Med.
- 1997 Mar;29(1):71-79.
In this study, we determined proMMP-2 activating capacity of membrane extract prepared from the tissue of invasive ductal carcinoma of breast by zymogram gel analysis. We compared the effect of... -
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- Hormonal regulation of ICAM-1 gene expression in thyroid cells, FRTL-5
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An BS, Ku BJ, Park SY, Shin JK, Lee JH, Kim YK, Shong MH, Ro HK
- KMID: 2128625
- Exp Mol Med.
- 1997 Mar;29(1):45-51.
Our previous works have shown that human thyroid follicular cells from Graves' disease and FRTL-5 rat thyroid cells express the intercellular adhesion molecule-1 (ICAM-1) molecule and its expression is upregulated... -
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- Production of IL-12 from gene modified human dermal fibroblasts: A preclinical study for IL-12 cancer gene therapy
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Park CH, Kang WK, Oh MS, Kim WS, Yang JH, Lotze MT, Kim SY, Park K, Park CH
- KMID: 2128628
- Exp Mol Med.
- 1997 Mar;29(1):65-69.
Cytokine has been used as an immune stimulator and administered to patients for a treatment of cancer. Interleukin-12 (IL-12) is a potent cytokine which acts through a variety of functions... -
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- Protein methylation in cellular proliferation and differentiation: Non-histone nuclear methyl acceptor protein(s) during 3'-methyl-4-dimethylaminoazobenzeneinduced hepatocarcinogenesis
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Paik MK, Han YJ, Hong JH, Kim JS, Suh KS, Yoon SJ
- KMID: 2128624
- Exp Mol Med.
- 1997 Mar;29(1):35-43.
An accelerating effect of methyl-deficient diet (MDD) on hepatocarcinogenesis and methylation pattern of nuclear protein(s) by S-adenosylmethionine: protein arginine N-methyltransferase (protein methylase I, PM-I) have been studied with 3'-methyl-4-dimethyl- aminoazobenzene(MeDAB)-treated... -
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