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Effects of overexpression of stimulatory G proteins on the expression of the other G proteins in COS-1 cells

Kim SY, Jang IS, Yang JM, Kwak SJ, Juhnn YS

  • KMID: 2045610
  • Exp Mol Med.
  • 1997 Jun;29(2):133-137.
To investigate the interaction of stimulatory GTP binding protein (G(s)) pathways with others, we overexpressed wild type alpha subunit of G(s) (G(s) alpha), constitutively activated R201E G(s) alpha, and dominant...
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Species specificity of a novel factor which augments the expression of MHC class I antigens on tumor cell lines

Puri N, Raval A, Saxena RK

  • KMID: 2045609
  • Exp Mol Med.
  • 1997 Jun;29(2):129-132.
A novel factor which augments the expression of major histocompatibility complex I (MHC augmenting factor or MHC-AF) antigens on tumor cell lines, has been isolated from the culture supernatants of...
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Differential expression of proteins related to START checkpoint of the cell cycle in human stomach, lung, cervix and liver cancers

Kim JR, Kim SY, Kim MJ, Kim JH

  • KMID: 2045608
  • Exp Mol Med.
  • 1997 Jun;29(2):123-128.
START (restriction) checkpoint in late G1 of the cell cycle is important in the regulation of cell proliferation. Many tumors have shown abnormalities partly in the components such as p53,...
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Cytotoxicity of Vibrio vulnificus cytolysin on pulmonary endothelial cells

Kim JS

  • KMID: 2045607
  • Exp Mol Med.
  • 1997 Jun;29(2):117-121.
The cytolysin produced by V. vulnificus has been known to cause lethality by increasing pulmonary vascular permeability in mice. In the present study, its cytotoxic mechanism on CPAE cell, a...
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Lactoferrin as a gene delivery vehicle to hepatocytes

Oh ST, Rih JK, Kwon HS, Hwang DS, Kim SY, Yim JB

  • KMID: 2045606
  • Exp Mol Med.
  • 1997 Jun;29(2):111-116.
Using lactoferrin as the specific ligand, we developed a simplified method for preparation of molecular conjugate for gene delivery. Replacement of column chromatography and dialysis by one step centrifugal filtration...
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A simple human immunodeficiency virus vector system for selective infection of CD4(+) cells and inducible expression of foreign genes

Kim YS

  • KMID: 2045605
  • Exp Mol Med.
  • 1997 Jun;29(2):103-110.
The alteration of T lymphocyte functions as a consequence of human immunodeficiency virus (HIV) infection is a potential target for the genetic treatment of the acquired immunodeficiency syndrome (AIDS). One...
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Structure of heavy and light chains of blood coagulation factor VIII (FVIII) involved in the activation of FVIII

Oh SH, Kim HW, Kim YJ

  • KMID: 2045604
  • Exp Mol Med.
  • 1997 Jun;29(2):97-102.
Structure of human blood coagulation factor VIII (FVIII) in relation to its activation process was investigated. FVIII was purified from a commercial FVIII concentrate by immunoaffinity chromatography and its dissociated...
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Biological roles of insulin-like growth factor binding proteins (IGFBPs)

Kim HS, Rosenfeld , Oh YM

  • KMID: 2045603
  • Exp Mol Med.
  • 1997 Jun;29(2):85-96.
The insulin-like growth factor binding protein (IGFBP) family is a critical component of the insulin-like growth factor (IGF) system which regulate the biological actions of the IGFs and may also...
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