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A simple protocol of DNA sequencing with 10% formamide for dissolving G/C compression

Kang KR, Kim YW

  • KMID: 1532668
  • Exp Mol Med.
  • 1997 Dec;29(4):235-237.
Formamide has been widely used in urea/polyacrylamide gel to solve the compression problems that are occasionally found during the DNA sequencing of G/C rich regions. In this study, however, 10%...
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Phosphorylation of chicken protein tyrosine phosphatase 1 by casein kinase II in vitro

Jung EJ, Kang KR, Kang YS

  • KMID: 1532667
  • Exp Mol Med.
  • 1997 Dec;29(4):229-233.
The phosphorylation and dephosphorylation of proteins on tyrosyl residues are key regulatory mechanisms of cell growth and signal transduction and are controlled by opposing activities of protein tyrosine kinases and...
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Expression of signal transducing G proteins in human melanoma cell lines

Lee ES, Kang WH, Jin YH, Juhnn YS

  • KMID: 1532666
  • Exp Mol Med.
  • 1997 Dec;29(4):223-227.
Some malignant melanoma cells regress spontaneously by terminal differentiation, and understanding the mechanisms of this spontaneous regression can contribute to the development of a new therapy not only for melanoma...
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Structure of human voltage-dependent calcium channel (VDCC) beta 3 subunit gene

Chang YJ, Cho KH, Hong YS, Lee SM, Kim HL

  • KMID: 1532665
  • Exp Mol Med.
  • 1997 Dec;29(4):217-221.
In excitable and endocrine organs, calcium influxes through the voltage-dependent calcium channel (VDCC), composed of four (alpha 1, alpha 2, beta, and gamma) subunits. Four isoforms of beta subunits (beta...
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The effects of various hormones and growth factors on the growth of human insulin-producing cell line in serum-free medium

Lee JJ, Kwon JH, Park YK, Kwon O, Yoon TW

  • KMID: 1532664
  • Exp Mol Med.
  • 1997 Dec;29(4):209-216.
An insulin-producing cell line, HE, was derived from immortalized human pancreatic p-cells transformed by SV40 DNA, To make serum free medium specific for the cells, it was necessary to select...
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Stimulation of c-myc protooncogene expression by transforming growth factor a in human ovarian cancer cells

Choi JY, Hong YS, Park HY

  • KMID: 1532663
  • Exp Mol Med.
  • 1997 Dec;29(4):203-208.
To investigate whether transforming growth factor alpha (TGF alpha) treatment of human ovarian cancer cells was associated with the induction of c-myc protooncogene, the expression of this gene in NIH:OVCAR-3...
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Thiosulfate sulfurtransferase and UDP-glucuronosyltransferase activities in cholestatic rat liver induced by common bile duct ligation

Ihm JS, Kim YH

  • KMID: 1532662
  • Exp Mol Med.
  • 1997 Dec;29(4):197-201.
We have investigated the effect of cholestasis on the hepatic thiosulfate sulfurtransferase (rhodanese) and UDP-glucuronosyltransferase (UDP-GT) activities in rats. Rhodanese activities in the liver cytosol, mitochondria and microsomal fractions as...
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Effect of organosulfur compounds on the expression of UDP-glucuronosyltransferase and thyroid hormone level in TCDD-treated rats

Hong YS, Kim HL

  • KMID: 1532661
  • Exp Mol Med.
  • 1997 Dec;29(4):191-196.
In this study, we investigated the effect of organosulfur compounds including, diallyl sulfide (DAS), garlic extract, and dially disulfide (DADS) on inducible expression of UDP-glucuronosyltransferase (UGT1) and thyroid hormone level...
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