- Cloning and characterization of 5'-upstream region of human phospholipase C-beta2 gene
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Yun ES, Lee SJ, Kim MJ, Ryu SH, Suh PG
- KMID: 1085743
- Exp Mol Med.
- 2001 Jun;33(2):76-82.
5'-upstream region of the phospholipase C-beta2 gene, 810 bp, was cloned and characterized. S1 nuclease mapping and primer extension analyses revealed that a single transcriptional start site locates at 284... -
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- An enzymatic method for the detection of human serum albumin
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Javed MU, Waqar SN
- KMID: 1085747
- Exp Mol Med.
- 2001 Jun;33(2):103-105.
Albumin is the most abundant protein in human serum. A dye-binding method is commonly used in clinical laboratories for its estimation using different types of dyes. However, all these dye... -
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- The protective effect of Amomum xanthoides extract against alloxan-induced diabetes through the suppression of NFkappaB activation
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Park BH, Park JW
- KMID: 1085741
- Exp Mol Med.
- 2001 Jun;33(2):64-68.
This study was undertaken to investigate the preventive mechanism of Amomum xanthoides extract against the development of alloxan-induced diabetics of mice. Pretreatment of mice with A. xanthoides extract via intraperitoneum... -
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- Cell-free expression and functional reconstitution of CALM in clathrin assembly
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Kim JA, Kim HL
- KMID: 1085745
- Exp Mol Med.
- 2001 Jun;33(2):89-94.
Clathrin-mediated vesicle formation is an essential step in the intracellular trafficking of the protein and lipid. Binding of clathrin assembly protein to clathrin triskelia induces their assembly into clathrin-coated vesicles... -
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- HNF1 and/or HNF3 may contribute to the tissue specific expression of glucokinase gene
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Cha JY, Kim HI, Im SS, Li TZ, Ahn YH
- KMID: 1085740
- Exp Mol Med.
- 2001 Jun;33(2):59-63.
A possible role of hepatocyte nuclear factor 1 (HNF1) or HNF3, a predominant trans-acting factors of hepatic or pancreatic beta-cells, was examined on the tissue specific interdependent expression of glucokinase... -
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- Homozygous VN (677C to T) and d/D (2756G to A) variants in the methylenetetrahydrofolate and methionine synthase genes in a case of hyperhomocysteinemia with stroke at young age
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Song KS, Song JW, Choi JR, Kim HK, Shin JS, Kim JH
- KMID: 1085748
- Exp Mol Med.
- 2001 Jun;33(2):106-109.
Hyperhomocysteinemia is known to be associated with an increased risk of myocardial infarction, stroke, peripheral arterial disease, and venous thrombosis. Gene polymorphisms in methylenetetrahydrofolate reductase (MTHFR) and methionine synthase (MS)... -
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- A novel method using edge detection for signal extraction from cDNA microarray image analysis
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Kim JH, Kim HY, Lee YS
- KMID: 1085744
- Exp Mol Med.
- 2001 Jun;33(2):83-88.
Gene expression analyses by probes of hybridization from mRNA to cDNA targets arrayed on membranes or activated glass surfaces have revolutionized the way of profiling mega level gene expression. The... -
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- Production and characterization of monoclonal antibodies against amphiphysins
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Jin YL, Kim KY, Soung NK, Shin EY, Kim EG, Kim SR
- KMID: 1085742
- Exp Mol Med.
- 2001 Jun;33(2):69-75.
Amphiphysin I and II, proteins enriched in nerve terminals, form heterodimers and interact with dynamin and synaptojanin through their Src homology 3 (SH3) domain. In order to study the expression... -
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- Potential role of leptin in angiogenesis: leptin induces endothelial cell proliferation and expression of matrix metalloproteinases in vivo and in vitro
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Park HY, Kwon HM, Lim HJ, Hong BK, Lee JY, Park BE, Jang YS, Cho SY, Kim HS
- KMID: 1085746
- Exp Mol Med.
- 2001 Jun;33(2):95-102.
Leptin, the product of ob gene, is an endocrine hormone that regulates adipose tissue mass. Recently, leptin has been found to generate a growth signal involving a tyrosine kinase-dependent intracellular... -
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