- The ontogeny of excitatory amino acid receptors in the rat brain quantitative autoradiographic study: I. N-methyl-D-aspartate receptors
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Lee HS
- KMID: 1686775
- Korean J Anat.
- 1991 Sep;24(3):344-355.
No abstract available. -
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- The Change of Taurine in The Transient Global Ischemic Rabbit
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Shin SW, Kim HK, Baik SW, Seo KS, Kim IS, Chung KS
- KMID: 2236900
- Korean J Anesthesiol.
- 1996 Dec;31(6):698-705.
- doi: 10.4097/kjae.1996.31.6.698
BACKGROUNDS: The importance of toxic extracellular levels of excitatory amino acids, as well as of high extracellular levels of inhibitory amino acids, is considered to be related with the pathophysiology... -
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- The Effect of Ketamine Anesthesia on the Formation of Brain Edema During Focal Ischemia in Rats
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Oh SM, Choi SK, Kang SK
- KMID: 2067858
- J Korean Neurosurg Soc.
- 1990 Dec;19(10-12):1397-1404.
Excitatory amino acids have been implicated as one of the important putative cellular toxins in ischemic brain. Ketamine antagonizes the excitotoxic action of excitatory amino acids in the central nervous... -
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- Studies on Amino Acids Pattern in Amyotrophic Lateral Sclerosis
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Lee KW, Kim BM, Ju IS, Um TH, Hong YJ, Kim JQ
- KMID: 2065971
- J Korean Neurol Assoc.
- 1995 Mar;13(1):32-38.
Recent researches on ALS pathogenesis are focusing on abnormal immunological factors, excitotoxic substances, neurotrophic factors, and oxidative stress. It is well known that glutamate and aspartate are major putative excitatory... -
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- Involvement of NMDA Receptor and L-type Calcium Channel in the Excitatory Action of Morphine
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Koo BS, Shin HK, Kang SH, Jun JH
- KMID: 2285258
- Korean J Physiol Pharmacol.
- 2002 Oct;6(5):241-246.
We studied the excitatory action of morphine on the responses of dorsal horn neuron to iontophoretic application of excitatory amino acid and C-fiber stimulation by using the in vivo electrophysiological... -
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- Glutamate Levels in the Vitreous Body of an In Vivo Model of Optic Nerve Ischemia
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Choung HK, Kim TW, Park KH, Kim DM
- KMID: 2205859
- J Korean Ophthalmol Soc.
- 2000 Apr;41(4):863-870.
To explore the possibility that an elevation of glutamate in the vitreous might be associated with the microvascular compromise of the optic nerve, endothelin1(ET-1)in a dosage of 0.1 microgram/day(5 rabbits)or... -
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- Three Cases of Typical Clinical Characteristics and Overview of Neuroleptic Malignant Syndrome
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Lee KK, Kim HW
- KMID: 1944957
- J Korean Soc Biol Psychiatry.
- 1997 Jun;4(1):136-145.
We are report on three cases of typical clinical characterstics and treatment response in neuroleptic maligant syndrome(NMS), and reviewed the literatures of NMS. NMS was first recognized as a life-threatening... -
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- Magnesium suppresses the responses of dorsal horn cell to noxious stimuli in the rat
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Shin HK, Kim JH, Kim KS
- KMID: 2285217
- Korean J Physiol Pharmacol.
- 1999 Jun;3(3):237-244.
Magnesium ion is known to selectively block the N-methyl-D-aspartate (NMDA)-induced responses and to have anticonvulsive action, neuroprotective effect and antinociceptive action in the behavioral test. In this study, we investigated the effect of... -
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- The Effects of Repeated Toluene Exposure on Amino Acid Neurotransmitters in the Rat Brain
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Kim HK, Baeck SK, Ryu SJ, Kim IS
- KMID: 2228770
- Korean J Crit Care Med.
- 1998 Jun;13(1):33-42.
Introduction: It was aimed to investigate the effect of chronic toluene exposure on amino acid neurotransmitters in the rat brain, corpus striatum. METHODS: Twenty four male Sprague-Dawley rats were divided... -
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- Zn2+ modulates the responses of rat dorsal horn neuron to C-fiber stimulation and excitatory amino acids
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Ahn CH, Shin HK, Kim JH
- KMID: 1581023
- Korean J Physiol Pharmacol.
- 2000 Dec;4(6):455-461.
Zinc contained in the neurons of central nervous system is activity-dependently released and then attenuates NMDA (N-methyl-D-aspartate)-induced neurotoxicity while augmenting non-NMDA-induced neurodegeneration. Zinc also has been reported to produce antinociceptive action on the inflammation-... -
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- The Stereotaxic Injection of Kainic Acid into Corpus Striatum: Destruction of Neuron with Sparing Axon
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Ahn BC, Kim DE, Kwon OS, Kim KY, Lee WB, Kim DC
- KMID: 2065921
- J Korean Neurol Assoc.
- 1991 Sep;9(3):315-322.
The ultrastructure of the excitotoxic lesion similar to that occurring in the degenerative neuronal disease was produceby stereotaxic injections of 1 nmol and 10 mnol of kainic acid nto the... -
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- Changes in Concentration of Extracellular Aspartate and Glutamate During Cortical Spreading Depression in the Rat Cerebral Cortex
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Song JH, Park YK, Chung YG, Chung HS, Suh JK, Lee KC, Lee HK
- KMID: 2018871
- J Korean Neurosurg Soc.
- 1996 Feb;25(2):242-251.
The author has examined the effect of cortical spreading depression(CSD) on the changes in extracellular concetration of aspartate and glutamate in the neocortex of anesthetized rats using microdialysis and high... -
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- Calcium modulates excitatory amino acid (EAA)- and substance P-induced rat dorsal horn cell responses
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Shin HK, Kang SH, Chung ID, Kim KS
- KMID: 1917068
- Korean J Physiol Pharmacol.
- 1999 Feb;3(1):35-45.
Excitatory amino acid (EAA) and substance P (SP) have been known to be primary candidates for nociceptive neurotransmitter in the spinal cord, and calcium ions are implicated in processing of the sensory informations... -
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- The Role of Peripheral N-Methyl-D-Aspartate (NMDA) Receptors in Freund's Complete Adjuvant Induced Mechanical Hyperalgesia in Rats
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Lim TH, Kang SS, Song JG, Choi Y
- KMID: 2091590
- Korean J Anesthesiol.
- 2000 Dec;39(6):S35-S40.
- doi: 10.4097/kjae.2000.39.6.S35
BACKGROUND: While the effects of excitatory amino acids have been characterized in the central nervous system, relatively little is known about their possible modulation of elements responsible for hyperalgesia within... -
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- Experimental Study of Initiation of Cortical Spreading Depression by Excitatory Amino Acids Using a New Topical Application Model
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Park JY, Park YK, Chung YG, Chung HS, Lee KC, Lee HK
- KMID: 2010223
- J Korean Neurosurg Soc.
- 1996 Mar;25(3):462-472.
The purpose of this study was, first, to devise a new model for topical application of excitatory amino acids(EAAs) to rat cerebral cortex that successfully and repeatdly initiate the cortical... -
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- Regulation of immediate early gene expression by glutamate receptor activation in C6 rat glioma cells
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Lee JK, Kim YH, Choi SS, Suh HW
- KMID: 1606834
- Korean J Physiol Pharmacol.
- 2001 Feb;5(1):19-25.
We have studied the effects of excitatory amino acids on the expression of the c-fos and c-jun mRNA in rat C6 glioma cells. The glutamate, N-methyl-D-aspartate (NMDA), and kainic acid (KA) increased... -
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- Apoptotic process is involved in the L-glutamate-induced PC12 cell death
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Sung KW, Jung KH, Kim SY, Kang JH, Lee SB
- KMID: 2285188
- Korean J Physiol Pharmacol.
- 1997 Dec;1(6):699-705.
Although it is known that neuronal cell death during development occurs by apoptosis, the mechanisms underlying excitatory amino acid-induced neuronal cell death remain poorly understood. In this study we have examined the mechanism... -
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- Antinociceptive Actions of Excitatory Amino Acid Recetor Antagonists in the Spinal Cord of a Rat Model for Neuropathic Pain
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Lee SA, Leem JW, Park ES, Choi EJ, Nam TS, Paik KS
- KMID: 1957218
- J Korean Neurol Assoc.
- 1995 Sep;13(3):438-452.
It has been proposed that excitatory amirio acid (EAA) receptors mediate sensitimtion of central neurons that may play a cruc ial role in the generation of neuropathic pain. We performed... -
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- The Effects of Intrathecal Ketamine and NBQX on Neurologic Injury and Spinal Cord Glutamate Receptor mRNA Expression in Transient Spinal Ischemia in the Rat
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Baek SH, Hong JM, Chung KS
- KMID: 1590022
- Korean J Crit Care Med.
- 2005 Jun;20(1):24-31.
BACKGROUND: Spinal cord injury occurring as the result of surgical repair of thoracic and thoracoabdominal aortic disease remains a devastating complication. Excitatory amino acids have been known to cause neurologic... -
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- Responsiveness of dendrites to the glutamate applied focally with pressure ejector and iontophoresis into hippocampal slices
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Kim JH, Shin HK, Chang HJ, Kim HY
- KMID: 1607134
- Korean J Physiol Pharmacol.
- 2001 Dec;5(6):457-466.
Glutamate is the most common excitatory amino acid in the brain. Responsiveness of dendrites to the glutamate greatly varies depending on the application sites. Especially, a point of the maximal... -
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