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Serum Neurofilament Light Chain Is Associated with Incident Lacunes in Progressive Cerebral Small Vessel Disease

Peters N, van Leijsen E, Tuladhar AM, Barro C, Konieczny MJ, Ewers M, Lyrer P, Engelter ST, Kuhle J, Duering M, de Leeuw FE

Background and Purpose Serum neurofilament light (NfL)-chain is a circulating marker for neuroaxonal injury and is also associated with severity of cerebral small vessel disease (SVD) cross-sectionally. Here we explored...
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Serum Neurofilament Light Chain Levels Are Related to Small Vessel Disease Burden

Duering M, Konieczny , Tiedt S, Baykara E, Tuladhar A, van Leijsen E, Lyrer P, Engelter S, Gesierich , Achmüller M, Barro C, Adam R, Ewers M, Dichgans M, Kuhle J, de Leeuw F, Peters N

BACKGROUND AND PURPOSE: Neurofilament light chain (NfL) is a blood marker for neuroaxonal damage. We assessed the association between serum NfL and cerebral small vessel disease (SVD), which is highly...
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