- Erratum: Chlorogenic Acid Improves Neuroprotective Effect of PEP-1-Ribosomal Protein S3 Against Ischemic Insult
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Ahn EH, Kim DW, Shin MJ, Kwon SW, Kim YN, Kim DS, Lim SS, Kim J, Park J, Eum WS, Hwang HS, Choi SY
- KMID: 2165419
- Exp Neurobiol.
- 2012 Dec;21(4):172-172.
- doi: 10.5607/en.2012.21.4.172
On page 173, the incorrect image which was not submitted by the author was mistakenly printed for Fig. 5 by a system error of the editing company. -
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- Retraction: Protective effects of transduced Tat-DJ-1 protein against oxidative stress and ischemic brain injury
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Jeong HJ, Kim DW, Kim MJ, Woo SJ, Kim HR, Kim SM, Jo HS, Hwang HS, Kim DS, Cho SW, Won MH, Han KH, Park J, Eum WS, Choi SY
- KMID: 2154243
- Exp Mol Med.
- 2013 May;45(5):e24.
No abstract available. -
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- Effects of p-chlorophenylalanine on the synthesis of pancreatic amylase in rats
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Kwon HY, Eum WS, Jang HW, Lee YL, Park HJ
- KMID: 1982599
- Korean J Physiol Pharmacol.
- 2000 Apr;4(2):129-135.
Previously, we have reported that p-chlorophenylalanine (PCPA), a serotonin depletor, profoundly increased pancreatic fluid and bicarbonate secretion but remarkably inhibited pancreatic amylase secretion in anesthetized rats. The present study was performed to verify the... -
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- Dexamethasone-induced differentiation of pancreatic AR42J cell involves p21(waf1/cip1)and MAP kinase pathway
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Eum WS, Li MZ, Sin GS, Choi SY, Park JB, Lee JY, Kwon HY
- KMID: 1093610
- Exp Mol Med.
- 2003 Oct;35(5):379-384.
Dexamethasone converts pluripotent pancreatic AR42J cells into exocrine cells expressing digestive enzymes. In order to address molecular mechanism of this differentiation, we have investigated the role of mitogen-activated protein (MAP)... -
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- Differential regulation of inducible nitric oxide synthase and cyclooxygenase-2 expression by superoxide dismutase in lipopolysaccharide stimulated RAW 264.7 cells
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Lee JA, Song HY, Ju SM, Lee SJ, Kwon HJ, Eum WS, Jang SH, Choi SY, Park J
- KMID: 756206
- Exp Mol Med.
- 2009 Sep;41(9):629-637.
- doi: 10.3858/emm.2009.41.9.069
Inducible nitric oxide synthase (iNOS) and cyclooxygenase 2 (COX-2) have been known to be involved in various pathophysiological processes such as inflammation. This study was performed to determine the regulatory... -
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- Transduction of Tat-Superoxide Dismutase into Insulin-producing MIN6N Cells Reduces Streptozotocin-induced Cytotoxicity
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Choung IS, Eum WS, Li MZ, Sin GS, Kang JH, Park J, Choi SY, Kwon HY
- KMID: 2071591
- Korean J Physiol Pharmacol.
- 2003 Jun;7(3):163-168.
The reactive oxygen species (ROS) are considered to be an important mediator in pancreatic beta cell destruction, thereby triggering the development of insulin-dependent diabetes mellitus. In the present study, HIV-1... -
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- Chlorogenic Acid Improves Neuroprotective Effect of PEP-1-Ribosomal Protein S3 Against Ischemic Insult
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Ahn EH, Kim DW, Shin MJ, Kwon SW, Kim YN, Kim DS, Lim SS, Kim J, Park J, Eum WS, Hwang HS, Choi SY
- KMID: 1495346
- Exp Neurobiol.
- 2011 Dec;20(4):169-175.
- doi: 10.5607/en.2011.20.4.169
Chlorogenic acid (CGA) possesses various biological activities such as anti-oxidant, anti-inflammatory, and anti-diabetic activities. In the present study, we examined the effect of CGA on the transduction efficiency of PEP-1-ribosomal... -
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- Protective Role of Transduced Tat-Thioredoxin1 (Trx1) against Oxidative Stress-Induced Neuronal Cell Death via ASK1-MAPK Signal Pathway
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Yeo EJ, Eum WS, Yeo HJ, Choi YJ, Sohn EJ, Kwon HJ, Kim DW, Kim DS, Cho SW, Park J, Han KH, Lee KW, Park JK, Shin MJ, Choi SY
- KMID: 2515281
- Biomol Ther.
- 2021 May;29(3):321-330.
- doi: 10.4062/biomolther.2020.154
Oxidative stress plays a crucial role in the development of neuronal disorders including brain ischemic injury. Thioredoxin 1 (Trx1), a 12 kDa oxidoreductase, has anti-oxidant and anti-apoptotic functions in various... -
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- Suppression of HIV-1 Tat-induced monocyte adhesiveness by a cell-permeable superoxide dismutase in astrocytes
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Song HY, Ju SM, Lee JA, Kwon HJ, Eum WS, Jang SH, Choi SY, Park J
- KMID: 1091072
- Exp Mol Med.
- 2007 Dec;39(6):778-786.
HIV-1 Tat is considered to be one of key players to facilitate monocyte entry into the CNS, which is characteristic feature of AIDS-related encephalitis and dementia. This study was performed... -
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- Inhibition of LPS-induced cyclooxygenase 2 and nitric oxide production by transduced PEP-1-PTEN fusion protein in Raw 264.7 macrophage cells
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Lee SH, Lee YP, Kim SY, Jeong MS, Lee MJ, Kang HW, Jeong HJ, Kim DW, Sohn EJ, Jang SH, Kim YH, Kwon HJ, Cho SW, Park J, Eum WS, Choi SY
- KMID: 1072943
- Exp Mol Med.
- 2008 Dec;40(6):629-638.
- doi: 10.3858/emm.2008.40.6.629
Phosphatase and tensin homologue deleted on chromosome 10 (PTEN) is a tumor suppressor. Although it is well known to have various physiological roles in cancer, its inhibitory effect on inflammation... -
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- Transduced Tat-aldose Reductase Protects Hippocampal Neuronal Cells against Oxidative Stress-induced Damage
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Cho SB, Eum WS, Shin MJ, Kwon HJ, Park JH, Choi YJ, Park J, Han KH, Kang JH, Kim DS, Cho SW, Kim DW, Choi SY
- KMID: 2463716
- Exp Neurobiol.
- 2019 Oct;28(5):612-627.
- doi: 10.5607/en.2019.28.5.612
Aldose reductase (AR) protein, a member of the NADPH-dependent aldo-keto reductase family, reduces a wide range of aldehydes and enhances cell survival by inhibition of oxidative stress. Oxidative stress is... -
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- The Stimulatory Effect of Essential Fatty Acids on Glucose Uptake Involves Both Akt and AMPK Activation in C2C12 Skeletal Muscle Cells
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Park SY, Kim MH, Ahn JH, Lee SJ, Lee JH, Eum WS, Choi SY, Kwon HY
- KMID: 2285518
- Korean J Physiol Pharmacol.
- 2014 Jun;18(3):255-261.
- doi: 10.4196/kjpp.2014.18.3.255
Essential fatty acid (EFA) is known to be required for the body to function normally and healthily. However, the effect of EFA on glucose uptake in skeletal muscle has not... -
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- Human glutamate dehydrogenase is immunologically distinct from other mammalian orthologues
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Jang SH, Kim AY, Bahn JH, Eum WS, Kim DW, Park J, Lee KS, Kang TC, Won MH, Kang JH, Kwon OS, Yoon HY, Lee EY, Cho SW, Choi SY
- KMID: 1109312
- Exp Mol Med.
- 2003 Aug;35(4):249-256.
Five monoclonal antibodies (mAbs) that recognize human glutamate dehydrogenase (GDH) have been selected and designated as monoclonal antibodies hGDH60-6, hGDH60-8, hGDH63-10, hGDH63-11, and hGDH91-14. A total of five mAbs recognizing... -
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- Protective effects of transduced Tat-DJ-1 protein against oxidative stress and ischemic brain injury
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Jeong HJ, Kim DW, Kim MJ, Woo SJ, Kim HR, Kim SM, Jo HS, Hwang HS, Kim DS, Cho SW, Won MH, Han KH, Park J, Eum WS, Choi SY
- KMID: 1506222
- Exp Mol Med.
- 2012 Oct;44(10):586-593.
Reactive oxygen species (ROS) contribute to the development of a number of neuronal diseases including ischemia. DJ-1, also known to PARK7, plays an important role in transcriptional regulation, acting as... -
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