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Effects of prostaglandins on ethanol damage in primary cultured rat hepatocytes

Yang JM, Choi SW, Kim SS, Sun HS, Park DH, Han SB, Oh GT, Kim WM

  • KMID: 759062
  • Korean J Intern Med.
  • 1998 Feb;13(1):1-9.
OBJECTIVES: Several reports demonstrated that ethanol administration impairs the DNA synthesis in rat hepatocytes. Also, it has been demonstrated that prostaglandin (PG) helps prevent membrane damage by hepatotoxic chemicals. In ...
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Gastroprotective Effects of PMK-S005 against Ethanol-Induced Acute Gastric Damage in Rats

Choi YJ, Kim N, Lee JY, Nam RH, Seo JH, Lee S, Kim HJ, Choi YJ, Lee HS, Lee DH

BACKGROUND/AIMS: This study aimed to examine the gastroprotective effects of PMK-S005, which is a synthetic S-allyl-L-cysteine (SAC; a sulfur-containing amino acid), against acute ethanol-induced gastric damage in rats. METHODS: Sprague-Dawley rats...
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