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Esophageal Microbiota and Nutritional Intakes in Patients With Achalasia Before and After Peroral Endoscopic Myotomy

Jung DH, Youn YH, Kim DH, Lim CH, Lim HS, Moon HS, Lee JY, Park H, Hong SJ

  • KMID: 2528038
  • J Neurogastroenterol Motil.
  • 2022 Apr;28(2):237-246.
  • doi: 10.5056/jnm21057
Background/Aims The composition of the microbiota in the esophagus is only partially understood, especially in patients with achalasia. We aim to investigate the esophageal microbial community and nutritional intakes in patients...
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Effect of Drinking Warm Water on Esophageal Preparation Before Peroral Endoscopic Myotomy in Patients With Achalasia

Yoon HJ, Youn YH, Yoo SH, Jeon S, Park H

  • KMID: 2528037
  • J Neurogastroenterol Motil.
  • 2022 Apr;28(2):231-236.
  • doi: 10.5056/jnm21119
Background/Aims Food retention, which is a characteristic observed in patients with achalasia, can interfere with peroral endoscopic myotomy (POEM). However, there is no established guideline for esophageal preparation for POEM. A previous...
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Novel Diagnostic Criteria for Functional Esophageal Disorders

Jung KW

The diagnosis of functional esophageal disorders has evolved from conventional manometry in 1970s to high-resolution manometry in 2010s. The conventional manometry was based on linear plot, whereas newly developed high-resolution...
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Chicago Classification ver. 4.0: Diagnosis of Achalasia and Esophagogastric Junction Outflow Obstruction

Jung KW

Achalasia is a common esophageal motility disorder characterized by inappropriate relaxation of the lower esophageal sphincter and a loss of normal peristalsis in the esophageal body. The newly suggested Chicago...
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Long-term outcomes of surgery for oesophageal achalasia

Ng ZQ, Murphy B, Edmunds S, Whitby M, Tan JH, Archer S

Background: Long-term patient-reported outcomes following surgery for achalasia are lacking in the literature. The aim of this study was to evaluate both short- and long-term outcomes of the surgical management...
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Morphologic Changes in Esophageal Body Movement During Bolus Transport After Peroral Endoscopic Myotomy in Type III Achalasia

Kim AJS, Ong S, Kim JH, Lee HS, Yoon JS, Hur DY

  • KMID: 2523792
  • J Neurogastroenterol Motil.
  • 2022 Jan;28(1):131-144.
  • doi: 10.5056/jnm21020
Background/Aims The effect of peroral endoscopic myotomy (POEM) on esophageal body movement in achalasia is poorly understood. This study aims to evaluate morphological changes in esophageal body movement after POEM in...
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Role of Peroral Endoscopic Myotomy in Advanced Achalasia Cardia With Sigmoid and/or Megaesophagus: A Systematic Review and Metanalysis

Mandavdhare HS, Kumar M P, Shukla J, Kumar A, Sharma V

  • KMID: 2523780
  • J Neurogastroenterol Motil.
  • 2022 Jan;28(1):15-27.
  • doi: 10.5056/jnm21122
Background/Aims Sigmoid esophagus and/or megaesophagus are considered as an advanced stage in the natural history of achalasia cardia. The role of peroral endoscopic myotomy (POEM) in these subset of patients is...
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Histopathological Analysis of Esophageal Mucosa in Patients with Achalasia

Lee BE, Kim GH, Shin N, Park DY, Song GA

Background/Aims: Achalasia is an esophageal motor disorder that leads to functional esophageal obstruction. Food stasis and bacterial fermentation can predispose an individual to esophageal mucosal inflammation, causing multifocal dysplasia and...
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Esophageal Motility Patterns After Peroral Endoscopic Myotomy in Patients With Achalasia

Vackova Z, Mares J, Krajciova J, Rabekova Z, Zdrhova L, Loudova P, Spicak J, Stirand P, Hucl T, Martinek J

  • KMID: 2514678
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):205-214.
  • doi: 10.5056/jnm20126
Background/Aims Several studies have reported partial recovery of peristalsis in patients with achalasia after myotomy. The aim of our study is to analyze esophageal motility patterns after peroral endoscopic myotomy (POEM)...
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Efficacy and Safety of Peroral Endoscopic Myotomy in Achalasia Patients with Failed Previous Intervention: A Systematic Review and Meta-analysis

Tan S, Zhong C, Ren Y, Luo X, Xu J, Fu X, Peng Y, Tang X

Peroral endoscopic myotomy (POEM) has emerged as a rescue treatment for recurrent or persistent achalasia after failed initial management. Therefore, we aimed to investigate the efficacy and safety of POEM...
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Diagnosis of Dysphagia: High Resolution Manometry & EndoFLIP

Cha B, Jung KW

Esophageal motility disorders were re-defined when high-resolution manometry was employed to better understand their pathogenesis. Newly developed parameters including integrated relaxation pressure (IRP), distal contractile integral, and distal latency showed...
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Achalasia During Pregnancy: Proposed Management Algorithm Based on a Thorough Literature Review

Vosko S, Cohen DL, Neeman O, Matalon S, Broide E, Shirin H

  • KMID: 2510058
  • J Neurogastroenterol Motil.
  • 2021 Jan;27(1):8-18.
  • doi: 10.5056/jnm20181
Fewer than 40 cases of achalasia occurring in pregnant woman have been reported in the literature. Given the rarity of achalasia during pregnancy, and the numerous treatment options that are...
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Comparison of Short Versus Long Esophageal Myotomy in Cases With Idiopathic Achalasia: A Randomized Controlled Trial

Nabi Z, Ramchandani M, Sayyed M, Chavan R, Darisetty S, Goud R, Murthy HVV, Reddy DN

  • KMID: 2510063
  • J Neurogastroenterol Motil.
  • 2021 Jan;27(1):63-70.
  • doi: 10.5056/jnm20022
Background/Aims Per-oral endoscopic myotomy (POEM) is an established treatment for achalasia. The technique of POEM is still evolving and the impact of length of esophageal myotomy on the outcomes of POEM...
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A Case of Achalasia Presenting with Cardiac Arrest due to Left Atrial Compression

Yeom DH, Ryu HS

Achalasia is a rare primary esophageal motility disorder characterized by the loss of enteric neurons leading to an absence of peristalsis and impaired relaxation of the lower esophageal sphincter. The...
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Performing High-resolution Impedance Manometry After Endoscopy With Conscious Sedation Has Negligible Effects on Esophageal Motility Results

Su H, Carlson DA, Donnan E, Kou W, Prescott J, Decorrevont A, Shilati F, Masihi M, Pandolfino JE

  • KMID: 2504003
  • J Neurogastroenterol Motil.
  • 2020 Jul;26(3):352-361.
  • doi: 10.5056/jnm20006
Background/Aims High-resolution manometry (HRM) performed without sedation is the standard procedure. However, some patients cannot tolerate transnasal placement of the manometry catheter. We aim to assess the practice of performing...
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Characteristics of a Subset of Achalasia With Normal Integrated Relaxation Pressure

Kim E, Yoo IK, Yon DK, Cho JY, Hong SP

  • KMID: 2500685
  • J Neurogastroenterol Motil.
  • 2020 Apr;26(2):274-280.
  • doi: 10.5056/jnm19130
Background/Aims Integrated relaxation pressure (IRP) is a critical diagnostic criterion to define achalasia. However, there are some cases with typical symptoms and signs of achalasia but with normal IRP. The...
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Role of Rapid Drink Challenge During Esophageal High-resolution Manometry in Predicting Outcome of Peroral Endoscopic Myotomy in Patients With Achalasia

Foisy H, Pioche M, Chabrun E, Ponchon T, Zerbib F, Rivory J, Mion F, Roman S

  • KMID: 2500677
  • J Neurogastroenterol Motil.
  • 2020 Apr;26(2):204-214.
  • doi: 10.5056/jnm19135
Background/Aims Peroral endoscopy myotomy (POEM) is effective to treat achalasia. We aim to determine POEM effect on esophageal function and search for predictive factors of response to POEM and co-occurrence...
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2019 Seoul Consensus on Esophageal Achalasia Guidelines

Jung HK, Hong SJ, Lee OY, Pandolfino J, Park H, Miwa H, Ghoshal UC, Mahadeva S, Oshima T, Chen M, Chua ASB, Cho YK, Lee TH, Min YW, Park CH, Kwon JG, Park MI, Jung K, Park JK, Jung KW, Lim HC, Jung DH, Kim DH, Lim CH, Moon HS, Park JH, Choi SC, Suzuki H, Patcharatrakul T, Wu JCY, Lee KJ, Tanaka S, Siah KTH, Park KS, Kim SE, The Korean Society of Neurogastroenterology and Motility

  • KMID: 2500676
  • J Neurogastroenterol Motil.
  • 2020 Apr;26(2):180-203.
  • doi: 10.5056/jnm20014
Esophageal achalasia is a primary motility disorder characterized by insufficient lower esophageal sphincter relaxation and loss of esophageal peristalsis. Achalasia is a chronic disease that causes progressive irreversible loss of...
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Adverse events associated with third space endoscopy: Diagnosis and management

Chavan R, Nabi Z, Reddy DN

Third space endoscopy (TSE) is a ‘magnum opus’ in the field of therapeutic gastrointestinal (GI) endoscopy that has led to a paradigm shift in the management of various GI disorders....
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Two-Stage Peroral Endoscopic Myotomy for Sigmoid-Type Achalasia

Kim HS, Kim HK, Ko WJ

Peroral endoscopic myotomy (POEM) has been recently considered as the first treatment option for achalasia. The standard POEM procedures are often successful in most patients, but sometimes technical challenges are...
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