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1 Development of two novel nontoxic mutants of Escherichia coli heat-labile enterotoxin

Park EJ, Chang JH, Kim JS, Chung SI, Yum JS

KMID: 1029939
Exp Mol Med.
1999 Jun;31(2):101-107.

Escherichia coli heat-labile enterotoxin (LT) is composed of catalytic A and non-catalytic homo-pentameric B subunits and causes diarrheal disease in human and animals. In order to produce a nontoxic LT for vaccine...

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