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Obesity may be erythropoietin dose-saving in hemodialysis patients

El-Kannishy GM, Megahed AF, Tawfik MM, El-Said G, Zakaria RT, Mohamed NA, Taha EM, Ammar AA, Abd Eltawab AM, Sayed-Ahmed NA

BACKGROUND: In dialysis patients, the obesity-survival paradox still requires an explanation. Anemia and high doses of erythropoiesis-stimulating agents (ESAs) are associated with worse outcomes in the hemodialysis (HD) population. In...
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Treatment of renal anemia: Erythropoiesis stimulating agents and beyond

Biggar P, Kim GH

Anemia, complicating the course of chronic kidney disease, is a significant parameter, whether interpreted as subjective impairment or an objective prognostic marker. Renal anemia is predominantly due to relative erythropoietin...
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Regulation of the embryonic erythropoietic niche: a future perspective

Yumine A, Fraser ST, Sugiyama D

The production of red blood cells, termed erythropoiesis, occurs in two waves in the developing mouse embryo: first primitive erythropoiesis followed by definitive erythropoiesis. In the mouse embryo, both primitive...
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Genetically Engineered In Vitro Erythropoiesis

Geiler C, Andrade I, Clayton A, Greenwald

BACKGROUND: Engineered blood has the greatest potential to combat a predicted future shortfall in the US blood supply for transfusion treatments. Engineered blood produced from hematopoietic stem cell (HSC) derived...
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A mild decrease of renal function is related to increased hemoglobin level during 5-year follow-up period

Shin N, Kim H, Kim HJ, Han M, Lee S, Jo H, Hyuk H, Chin HJ

BACKGROUND/AIMS: We analyzed chronological changes in hemoglobin according to renal function changes over a 5-year follow-up period. METHODS: We enrolled 5,266 adults with a glomerular filtration rate (GFR) > or =...
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Exogenous c-Myc Blocks Differentiation and Improves Expansion of Human Erythroblasts In vitro

Geiler C, Andrade I, Greenwald

BACKGROUND: Engineered blood has the greatest potential to combat a predicted future shortfall in the blood supply for transfusion treatment. The production of red blood cells from hematopoietic stem cells...
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Frequency and Pattern of Hemoglobin Cycling in Korean Hemodialysis Patients Treated with Erythropoiesis Stimulating Agent

Hwang DS, Chung HC, Lee JH, Hwang YT, Seo JM, Lee JS, Park J

  • KMID: 2079747
  • Korean J Nephrol.
  • 2007 Jul;26(4):427-434.
PURPOSE: It is frequently observed that the level of hemoglobin (Hb) widely fluctuates during treatment of erythropoiesis stimulating agents (ESAs) in hemodialysis (HD) patients, known as Hb cycling. The purpose...
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Capsaicin promotes the development of burst-forming nits-erythroid (BFU-E) from mouse bone marrow cells

Lee SA, Ryu YS, Choi HI, Han IS

  • KMID: 1047078
  • Exp Mol Med.
  • 2007 Jun;39(3):278-283.
Capsaicin, the pungent component of chilli peppers, is known to induce mediators of hematopoiesis. We investigated the effect of capsaicin on hematopoiesis in mouse progenitor cells. Treatment of mouse bone...
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Defective Erythropoiesis in Bone Marrow is a Mechanism of Anemia in Children with Cancer

Kim MH, Lee JH, Wu CW, Cho SW, Lee KC

Evaluation of the mechanism of anemia in cancer patients might help to select patients for the more efficient use of erythropoietin (EPO, a growth factor for erythroid precursor cells). For...
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The Expression of Bcl-2 and Bax in Rat Hepatic Erythropoiesis

Chae HS, Bach JH, Yoo SJ, Kim DJ, Kim SS, Kim KY, Lee WB

  • KMID: 2030750
  • Korean J Anat.
  • 2002 Apr;35(2):143-152.
Hepatic erythropoiesis is a characteristic event of the fetal liver. Generally, the erythropoiesis shows 4 phases: developing (embryonic day (ED) 10 to 14), maximum flat (ED 14 to 16), decreasing...
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Change of Erythropoiesis and Serum Transferrin Receptor Levels with Gestational Age in Healthy Pregnant Women

Choi JW, Im MW, Pai SH

  • KMID: 2083412
  • Korean J Hematol.
  • 2000 May;35(2):134-142.
BACKGROUND: To investigate the change of iron dynamics, erythropoiesis, and serum transferrin receptor (sTfR) concentration during pregnancy, we measured the reticulocyte subpopulations, reticulocyte maturity index (RMI) and sTfR concentration in...
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Expression of TGF-beta isoforms in the Human Fetal Hepatic Erythropoiesis

Kee SW, Kim YW, Kim SS, Kim KY, Lee WB

  • KMID: 2071840
  • Korean J Phys Anthropol.
  • 1999 Jun;12(1):23-32.
The expression patterns of transforming growth factor-betas (TGF-betas) were studied immunohis-tochemically in hepatic erythropoietic cells and hepatocytes of 3 human fetal livers from 21 to 26 gestation weeks. The results...
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Difference of Erythropoietic Activity and Soluble Transferrin Receptor Levels Between Male and Female Neonates

Choi JW, Pai SH

  • KMID: 2287748
  • J Clin Pathol Qual Control.
  • 1999 Dec;21(2):335-341.
BACKGROUND: To investigate the differences of erythropoietic activity between male and female neonates, we measured the reticulocyte subpopulations, reticulocyte maturation index (RMI) and soluble transferrin receptor (sTfR) concentration in normal...
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Congenital CMV Infection with Blueberry-muffin Skin Lesions Showing Dermal Erythropoiesis

Kim SJ, Lim MH, Lee SC, Won YH, Chun IK, Choi YR, Park CS

Blueberry muffin rashes occur in various diseases including TORCH syndrome, transfusion reactions, leukemia, hereditary spherocytosis and neonatal sepsis. We report a case of congenital CMV(cytomegalovirus) infection showing blueberry muffin skin...
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Studies on the Role of the Kidney in Erythropoiesis 1. An experimental Study on the Role of the Kidney in Erythropoiesis in Uremic Rabbits Using Radioacitve Iron(Fe59)

Choo KW, Hurh Y, Kim HJ

  • KMID: 2139719
  • Korean J Urol.
  • 1961 Dec;2(2):143-149.
The relationship between the kidney and erythropoiesis was investigated. Thirty-three rabbits were used of which nine rabbits were subjected to bilateral nephrectomy, eight to unilateral nephrectomy with ureter ligation of...
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