- Endoscopic Removal of an Impacted Fishhook That Was in the Esophagus for Two Months
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Bae SY, Lee JH, Kim HJ, Sung YK, Song SY, Kim JJ, Rhee JC
- KMID: 2243153
- Korean J Gastrointest Endosc.
- 2009 Aug;39(2):85-87.
An esophageal foreign body has clinical significance because it may cause serious complications such as esophageal perforation, mediastinitis and/or aorto-esophageal fistula. A prompt attempt to remove an esophageal foreign body... -
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- Effect of Triptolide and Cisplatin Combination on Apoptosis in AMC-HN4 Cells
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Nam YJ, Song DW, Yeo CK, Kim DE, Kim MS, Park JW
- KMID: 2141183
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2008 Oct;51(10):894-902.
BACKGROUND AND OBJECTIVES: Cisplatin (CP) is a widely used agent for chemotherapy of head and neck squamous cell carcinoma but some tumor cell shows resistance to CP. Accordingly, it is... -
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- Triptolide Inhibits the Proliferation of Immortalized HT22 Hippocampal Cells Via Persistent Activation of Extracellular Signal-Regulated Kinase-1/2 by Down-Regulating Mitogen-Activated Protein Kinase Phosphatase-1 Expression
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Koo HS, Kang SD, Lee JH, Kim NH, Chung HT, Pae HO
- KMID: 2066699
- J Korean Neurosurg Soc.
- 2009 Oct;46(4):389-396.
- doi: 10.3340/jkns.2009.46.4.389
OBJECTIVE: Triptolide (TP) has been reported to suppress the expression of mitogen-activated protein kinase (MAPK) phosphatase-1 (MKP-1), of which main function is to inactivate the extracellular signal-regulated kinase-1/2 (ERK-1/2), the... -
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- Developmental Toxicity by Exposure to Bisphenol A Diglycidyl Ether during Gestation and Lactation Period in Sprague-dawley Male Rats
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Hyoung UJ, Yang YJ, Kwon SK, Yoo JH, Myoung SC, Kim SC, Hong YP
- KMID: 1125678
- J Prev Med Public Health.
- 2007 Mar;40(2):155-161.
- doi: 10.3961/jpmph.2007.40.2.155
OBJECTIVES: Bisphenol A diglycidyl ether (BADGE) is the major component in commercial liquid epoxy resins, which are manufactured by co-reacting bisphenol A with epichlorohydrin. This study was performed to... -
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- Fanconi anemia screening by diepoxybutane and mitomicin C tests in Korean children with bone marrow failure syndromes
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Kook H, Cho D, Cho SH, Hong WP, Kim CJ, Park JY, Yoon WS, Ryang DW, Hwang TJ
- KMID: 1038443
- J Korean Med Sci.
- 1998 Dec;13(6):623-628.
- doi: 10.3346/jkms.1998.13.6.623
Fanconi anemia (FA) is an autosomal recessive disorder of progressive bone marrow failure in patients with congenital malformations. FA is different from acquired aplastic anemia (AA) in terms of... -
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- Triptolide downregulates human GD3 synthase (hST8Sia I) gene expression in SK-MEL-2 human melanoma cells
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Kwon HY, Kim SJ, Kim CH, Son SW, Kim KS, Lee JH, Do SI, Lee YC
- KMID: 1115269
- Exp Mol Med.
- 2010 Dec;42(12):849-855.
- doi: 10.3858/emm.2010.42.12.088
In this study, we have shown that gene expression of human GD3 synthase (hST8Sia I) is suppressed by triptolide (TPL) in human melanoma SK-MEL-2 cells. To elucidate the mechanism underlying... -
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- Triptolide-induced suppression of phospholipase D expression inhibits proliferation of MDA-MB-231 breast cancer cells
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Kang DW, Lee JY, Oh DH, Park SY, Woo TM, Kim MK, Park MH, Jang YH, Min DS
- KMID: 756211
- Exp Mol Med.
- 2009 Sep;41(9):678-685.
- doi: 10.3858/emm.2009.41.9.074
In spite of the importance of phospholipase D (PLD) in cell proliferation and tumorigenesis, little is known about the molecules regulating PLD expression. Thus, identification of small molecules inhibiting PLD... -
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- Acute Testis Toxicity of Bisphenol A Diglycidyl Ether in Sprague-Dawley Rats
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Yang YJ, Lee SY, Kim KY, Hong YP
- KMID: 1070497
- J Prev Med Public Health.
- 2010 Mar;43(2):131-137.
- doi: 10.3961/jpmph.2010.43.2.131
OBJECTIVES: Bisphenol A diglycidyl ether (BADGE) is a liquid compound obtained by condensation of two molecules of epichlorohydrin with one molecule of bisphenol A. General and reproductive toxicity with BADGE... -
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- Triptolide downregulates Rac1 and the JAK/STAT3 pathway and inhibits colitis-related colon cancer progression
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Wang Z, Jin H, Xu R, Mei Q, Fan D
- KMID: 1009393
- Exp Mol Med.
- 2009 Oct;41(10):717-727.
- doi: 10.3858/emm.2009.41.10.078
Triptolide, a diterpenoid triepoxide from the traditional Chinese medicinal herb Tripterygium wilfordii Hook. f., is a potential treatment for autoimmune diseases as well a possible anti-tumor agent. It inhibits proliferation... -
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- Triptolide inhibits ovarian cancer cell invasion by repression of matrix metalloproteinase 7 and 19 and upregulation of E-cadherin
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Zhao H, Yang Z, Wang X, Zhang X, Wang M, Wang Y, Mei Q, Wang Z
- KMID: 1401755
- Exp Mol Med.
- 2012 Nov;44(11):633-641.
Triptolide, a compound extracted from the traditional Chinese medicine preparation of Tripterygium wilfordii Hook F., has been reported to have anti-inflammatory and anti-cancer activities. However, its effect on ovarian cancer... -
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