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Multiple Effects of a Novel Epothilone Analog on Cellular Processes and Signaling Pathways Regulated by Rac1 GTPase in the Human Breast Cancer Cells

Zhang H, An F, Tang L, Qiu R

The epothilones are a class of microtubule inhibitors that exhibit a strong antitumor activity. UTD2 is a novel epothilone analog generated by genetic manipulation of the polyketide biosynthetic gene cluster....
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A Case Report of Breast Cancer with Extensive Pulmonary Lymphovascular Tumor Emboli

Yang Y, Choi Y, Beom SH, Kim JW, Joen YK, Kim NJ, Kim JH, Im SA, Lee KH

We describe a patient with breast cancer who relapsed with an extensive pulmonary lymphovascular tumor embolism. A 38-year-old female, who previously received neoadjuvant chemotherapy and curative resection of breast cancer,...
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