- Identifying Novel B Cell Epitopes within Toxoplasma gondii GRA6
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Wang Y, Wang G, Cai JP
- KMID: 2353572
- Korean J Parasitol.
- 2016 Aug;54(4):431-437.
- doi: 10.3347/kjp.2016.54.4.431
The study of antigenic epitopes from Toxoplasma gondii has not only enhanced our understanding of the structure and function of antigens, the reactions between antigens and antibodies, and many other... -
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- T-cell epitope specificity for Porphyromonas gingivalis heat shock protein in periodontitis
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Lee JY, Lee JY, Choi JI
- KMID: 1999776
- J Korean Acad Periodontol.
- 2003 Dec;33(4):543-553.
- doi: 10.5051/jkape.2003.33.4.543
Due to considerably high degree of sequence homology between bacterial and human heat shock proteins (hsp), it has been widely thought that this protein might be involved in autoimmune disease... -
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- Relationship between Poor Immunogenicity of HLA-A2-Restricted Peptide Epitopes and Paucity of Naive CD8+ T-Cell Precursors in HLA-A2-Transgenic Mice
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Choi YS, Lee DH, Shin EC
- KMID: 2150810
- Immune Netw.
- 2014 Aug;14(4):219-225.
- doi: 10.4110/in.2014.14.4.219
We examined the immunogenicity of H-2 class I-restricted and HLA-A2-restricted epitopes through peptide immunization of HLA-A2-transgenic mice that also express mouse H-2 class I molecules. All four of the tested... -
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- T Cell Epitope Analysis of Structural Protein of Adenovirus
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Hwang JW, Kim MH, Kim KH
- KMID: 1557251
- Korean J Immunol.
- 1998 Dec;20(4):435-442.
Thelper (Th) cells play a pivotal role in the regulation of immune responses. Since Th epitopes in adenovirus have not yet been defined, in this study, it was attempted to... -
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- Common antigenic determinants on human tumors detected by anti-fetal brain and anti-neuroblastoma monoclonal antibodies
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Lee HC, Oh JS, Shin BA, Kim JY, Kang SS, Lee JH, Woo JH
- KMID: 1690200
- Korean J Immunol.
- 1991 May;13(1):1-15.
No abstract available. -
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- Construction and Characterization of Recombinant Poliovirus that Delivers T-cell epitope
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Cho SP, Lee BY, Chung SI, Min MK
- KMID: 1551975
- J Korean Soc Virol.
- 1998 Jun;28(2):139-146.
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- Evaluation of Differential Antigenic Properties of Selected B - cell Epitopes from the HIV - 1 p24 Protein using Synthetic Peptides
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Shin SY, Park JH, Lee MK, Hahm KS
- KMID: 2083009
- Korean J Immunol.
- 1998 Mar;20(1):9-16.
The gag encoded p24 protein of human immunodeficiency virus-1 (HIV-1) is a major constitutent of the viral core, and is also known as one of the most immunodominant antigens in... -
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- Epitope specificity of Porphyromonas gingivalis heat shock protein for T-cell and/or B-cell in human atherosclerosis
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Bak JG, Kim SJ, Choi JI
- KMID: 1999798
- J Korean Acad Periodontol.
- 2003 Jun;33(2):179-191.
- doi: 10.5051/jkape.2003.33.2.179
Since periodontal infections are suggested as risk factors for the development of cardiovascular diseases, the present study was performed to evaluate the T cell immune responses specific to Porphylomonas gingivalis(P.... -
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- Engineering therapeutic antibodies targeting G-protein–coupled receptors
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Jo M, Jung ST
- KMID: 2361494
- Exp Mol Med.
- 2016 Feb;48(2):e207.
- doi: 10.1038/emm.2015.105
G-protein–coupled receptors (GPCRs) are one of the most attractive therapeutic target classes because of their critical roles in intracellular signaling and their clinical relevance to a variety of diseases, including... -
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- Recombinant influenza viruses as delivery vectors for hepatis B virus epitopes
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Song JM, Lee KH, Seong BL
- KMID: 2278791
- Clin Exp Vaccine Res.
- 2012 Jul;1(1):77-82.
- doi: 10.7774/cevr.2012.1.1.77
PURPOSE: Neuraminidase (NA) of influenza virus contains stalk region that shows a great deal of variability in both amino acid sequence and length. In this paper, we investigated generation of... -
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- Removal of Alpha-Gal Epitopes from Porcine Aortic Valve and Pericardium using Recombinant Human Alpha Galactosidase A
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Park S, Kim WH, Choi SY, Kim YJ
- KMID: 1783143
- J Korean Med Sci.
- 2009 Dec;24(6):1126-1131.
- doi: 10.3346/jkms.2009.24.6.1126
It has been reported that the immune response due to alpha-Gal epitopes is an important factor in tissue valve failure. The elimination of the interaction between the natural anti-Gal antibodies... -
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- Changes of Cytoskeletal System in Neurodegenerative Disease: Immunohistochemical Characterization of Neurofibrillary Changes Induced by Mitotic Spindle Inhibitors
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Koo H
- KMID: 1965100
- Ewha Med J.
- 1992 Mar;15(1):1-9.
- doi: 10.12771/emj.1992.15.1.1
In experimental neurogenerative diseases, aluminum(Al) intoxication and axotomized sensory neurons showed an abnormal accumulation of neurofilaments(NF) in the neuronal perikarya. These NF contain phosphorylated(ph) epitopes that are not detectable in... -
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- An Ultrastructural Examination of the Epitope Expression at Each Domain of Type VII Collagen in Patients with Epidermolysis Bullosa Acquisita
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Eun C, Moon SH, Lee CW
- KMID: 2302346
- Korean J Dermatol.
- 2006 Jan;44(1):8-14.
BACKGROUND: Epidermolysis bullosa acquisita (EBA) is an autoimmune disease characterized by circulating IgG autoantibodies which bind to the type VII collagen (C-VII). The major antigenic epitopes in C-VII, to which... -
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- Characterizing affinity epitopes between prion protein and beta-amyloid using an epitope mapping immunoassay
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Kang M, Kim SY, An SS, Ju YR
- KMID: 2154253
- Exp Mol Med.
- 2013 Aug;45(8):e34.
Cellular prion protein, a membrane protein, is expressed in all mammals. Prion protein is also found in human blood as an anchorless protein, and this protein form is one of... -
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- Removal of alpha-Gal Epitopes in Aortic Valve and Pericardium ofPig Using Green Coffee Bean alpha-Galactosidase
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Park S, Kim WH, Kim KH, Lee CH, Choi SY, Lee C, Oh SS, Kim KC, Kim YJ
- KMID: 1987451
- Korean J Thorac Cardiovasc Surg.
- 2008 Feb;41(1):12-24.
BACKGROUND: It is currently thought that tissue valve degeneration is related to an animal's immune response, which is mainly due to cell surface alpha-Gal epitopes. Cell surface alpha-Gal epitopes are... -
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- Identificaiton of Novel Immunogenic Human Papillomavirus Type 16 E7-Specific Epitopes Restricted to HLA-A*33;03 for Cervical Cancer Immunotherapy
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Kim S, Chung HW, Kong HY, Lim JB
- KMID: 2374187
- Yonsei Med J.
- 2017 Jan;58(1):43-50.
- doi: 10.3349/ymj.2017.58.1.43
PURPOSE: To identify new immunogenic HLA-A*33;03-restricted epitopes from the human papillomavirus (HPV) 16 E7 protein for immunotherapy against cervical cancer. MATERIALS AND METHODS: We synthesized fourteen overlapping 15-amino acid peptides and... -
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- Cytomegalovirus Infection and Memory T Cell Inflation
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Kim J, Kim AR, Shin EC
- KMID: 2168045
- Immune Netw.
- 2015 Aug;15(4):186-190.
- doi: 10.4110/in.2015.15.4.186
Cytomegalovirus (CMV) infection in healthy individuals is usually asymptomatic and results in latent infection. CMV reactivation occasionally occurs in healthy individuals according to their immune status over time. T cell... -
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- Carbohydrates as food allergens
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Soh JY, Huang CH, Lee BW
- KMID: 2397063
- Asia Pac Allergy.
- 2015 Jan;5(1):17-24.
- doi: 10.5415/apallergy.2015.5.1.17
The literature supports the notion that carbohydrate epitopes, on their own, do not contribute significantly to the induction of allergic reactions. They bind weakly to IgE antibodies and have been... -
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- Production and characterization of monoclonal antibodies to oxidized LDL
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Choi KH, Lee HS, Chung HK
- KMID: 754986
- Exp Mol Med.
- 1998 Mar;30(1):41-45.
Oxidized low density lipoprotein (LDL) seems to take a part in atherogenesis through direct interactions with macrophages, endothelial cells, and smooth muscle cells, and is thought to participate in renal glomerular injury.... -
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- IgE-Binding Epitope Mapping and Tissue Localization of the Major American Cockroach Allergen Per a 2
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Lee MF, Chang CW, Song PP, Hwang GY, Lin SJ, Chen YH
- KMID: 2166685
- Allergy Asthma Immunol Res.
- 2015 Jul;7(4):376-383.
- doi: 10.4168/aair.2015.7.4.376
PURPOSE: Cockroaches are the second leading allergen in Taiwan. Sensitization to Per a 2, the major American cockroach allergen, correlates with clinical severity among patients with airway allergy, but there... -
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