- Ionizing radiation induces blockade of c-Jun N-terminal kinasedependent cell death pathway in amanner correlated with p21Cip/WAF1 induction in primary cultured normal human fibroblasts
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Cho ES, Lee SB, Bae IH, Lee YS, Lee SJ, Um HD
- KMID: 1093463
- Exp Mol Med.
- 2005 Aug;37(4):282-289.
During radiotherapy of cancer, neighboring normal cells may receive sub-lethal doses of radiation. To investigate whether such low levels of radiation modulate normal cell responses to death stimuli, primary cultured... -
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- Change of telomerase activity in rectal cancer with chemoradiation therapy
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Kim HR, Kim YJ, Kim HJ, Kim SK, Lee JH
- KMID: 648118
- J Korean Med Sci.
- 2000 Apr;15(2):167-172.
- doi: 10.3346/jkms.2000.15.2.167
Telomerase, an enzyme associated with cellular immortality, is expressed by most malignant cells and is inactive in most normal somatic cells, with the exception of proliferative stem cells, germ cells... -
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- Involvement of protein kinase C pathway in UVC-stimulated phospholipase D2 activity in Vero 76 cells
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Kim S, Choi MS, Choi MU
- KMID: 1089451
- Exp Mol Med.
- 2005 Oct;37(5):418-426.
Phospholipase D (PLD) activity is known to be related to oxidant-induced cellular signaling and membrane disturbance. Previously, an induction of PLD activity in various cell lines by X-ray irradiation was... -
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- Low energy proton beam induces tumor cell apoptosis through reactive oxygen species and activation of caspases
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Lee KB, Lee JS, Park JW, Huh TL, Lee YM
- KMID: 1103595
- Exp Mol Med.
- 2008 Feb;40(1):118-129.
- doi: 10.3858/emm.2008.40.1.118
Proton beam is useful to target tumor tissue sparing normal cells by allowing precise dose only into tumor cells. However, the cellular and molecular mechanisms by which proton beam induces... -
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